Lucke AJ - Search Results

1

Insecticidal activities of histone deacetylase inhibitors against a dipteran parasite of sheep, Lucilia cuprina.

Bagnall NH, Hines BM, Lucke AJ, Gupta PK, Reid RC, Fairlie DP, Kotze AC. Bagnall NH, et al. Among authors: lucke aj. Int J Parasitol Drugs Drug Resist. 2017 Apr;7(1):51-60. doi: 10.1016/j.ijpddr.2017.01.001. Epub 2017 Jan 10. Int J Parasitol Drugs Drug Resist. 2017. PMID: 28110187 Free PMC article.

2

Inhibitors selective for HDAC6 in enzymes and cells.

Gupta PK, Reid RC, Liu L, Lucke AJ, Broomfield SA, Andrews MR, Sweet MJ, Fairlie DP. Gupta PK, et al. Among authors: lucke aj. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7067-70. doi: 10.1016/j.bmcl.2010.09.100. Epub 2010 Oct 12. Bioorg Med Chem Lett. 2010. PMID: 20947351

3

Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components.

Wheatley NC, Andrews KT, Tran TL, Lucke AJ, Reid RC, Fairlie DP. Wheatley NC, et al. Among authors: lucke aj. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7080-4. doi: 10.1016/j.bmcl.2010.09.096. Epub 2010 Sep 22. Bioorg Med Chem Lett. 2010. PMID: 20951583

4

Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice.

Chua MJ, Tng J, Hesping E, Fisher GM, Goodman CD, Skinner-Adams T, Do D, Lucke AJ, Reid RC, Fairlie DP, Andrews KT. Chua MJ, et al. Among authors: lucke aj. Int J Parasitol Drugs Drug Resist. 2021 Dec;17:118-127. doi: 10.1016/j.ijpddr.2021.08.006. Epub 2021 Aug 23. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34560571 Free PMC article.

5

Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1-3 in mesendoderm cell differentiation.

Sinniah E, Wu Z, Shen S, Naval-Sanchez M, Chen X, Lim J, Helfer A, Iyer A, Tng J, Lucke AJ, Reid RC, Redd MA, Nefzger CM, Fairlie DP, Palpant NJ. Sinniah E, et al. Among authors: lucke aj. Cell Rep. 2022 May 17;39(7):110818. doi: 10.1016/j.celrep.2022.110818. Cell Rep. 2022. PMID: 35584683 Free article.

6

Potent antimalarial activity of histone deacetylase inhibitor analogues.

Andrews KT, Tran TN, Lucke AJ, Kahnberg P, Le GT, Boyle GM, Gardiner DL, Skinner-Adams TS, Fairlie DP. Andrews KT, et al. Among authors: lucke aj. Antimicrob Agents Chemother. 2008 Apr;52(4):1454-61. doi: 10.1128/AAC.00757-07. Epub 2008 Jan 22. Antimicrob Agents Chemother. 2008. PMID: 18212103 Free PMC article.

7

Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

Sumanadasa SD, Goodman CD, Lucke AJ, Skinner-Adams T, Sahama I, Haque A, Do TA, McFadden GI, Fairlie DP, Andrews KT. Sumanadasa SD, et al. Among authors: lucke aj. Antimicrob Agents Chemother. 2012 Jul;56(7):3849-56. doi: 10.1128/AAC.00030-12. Epub 2012 Apr 16. Antimicrob Agents Chemother. 2012. PMID: 22508312 Free PMC article.

8

Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis.

Kim SH, Redvers RP, Chi LH, Ling X, Lucke AJ, Reid RC, Fairlie DP, Martin ACBM, Anderson RL, Denoyer D, Pouliot N. Kim SH, et al. Among authors: lucke aj. Dis Model Mech. 2018 Jul 6;11(7):DMM034850. doi: 10.1242/dmm.034850. Dis Model Mech. 2018. PMID: 29784888 Free PMC article.

9

Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class I HDAC Enzymes and Cancer Cell Proliferation.

Tng J, Lim J, Wu KC, Lucke AJ, Xu W, Reid RC, Fairlie DP. Tng J, et al. Among authors: lucke aj. J Med Chem. 2020 Jun 11;63(11):5956-5971. doi: 10.1021/acs.jmedchem.0c00230. Epub 2020 May 21. J Med Chem. 2020. PMID: 32383881

10

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates.

Mak JYW, Wu KC, Gupta PK, Barbero S, McLaughlin MG, Lucke AJ, Tng J, Lim J, Loh Z, Sweet MJ, Reid RC, Liu L, Fairlie DP. Mak JYW, et al. Among authors: lucke aj. J Med Chem. 2021 Feb 25;64(4):2186-2204. doi: 10.1021/acs.jmedchem.0c01967. Epub 2021 Feb 11. J Med Chem. 2021. PMID: 33570940

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