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Page 1
Pathogenic Mis-splicing of CPEB4 in Schizophrenia.
Ollà I, Pardiñas AF, Parras A, Hernández IH, Santos-Galindo M, Picó S, Callado LF, Elorza A, Rodríguez-López C, Fernández-Miranda G, Belloc E, Walters JTR, O'Donovan MC, Méndez R, Toma C, Meana JJ, Owen MJ, Lucas JJ. Ollà I, et al. Among authors: lucas jj. Biol Psychiatry. 2023 Aug 15;94(4):341-351. doi: 10.1016/j.biopsych.2023.03.010. Epub 2023 Mar 22. Biol Psychiatry. 2023. PMID: 36958377 Free article.
Huntington's disease is a four-repeat tauopathy with tau nuclear rods.
Fernández-Nogales M, Cabrera JR, Santos-Galindo M, Hoozemans JJ, Ferrer I, Rozemuller AJ, Hernández F, Avila J, Lucas JJ. Fernández-Nogales M, et al. Among authors: lucas jj. Nat Med. 2014 Aug;20(8):881-5. doi: 10.1038/nm.3617. Epub 2014 Jul 20. Nat Med. 2014. PMID: 25038828 Free article.
Tau-positive nuclear indentations in P301S tauopathy mice.
Fernández-Nogales M, Santos-Galindo M, Merchán-Rubira J, Hoozemans JJM, Rábano A, Ferrer I, Avila J, Hernández F, Lucas JJ. Fernández-Nogales M, et al. Among authors: lucas jj. Brain Pathol. 2017 May;27(3):314-322. doi: 10.1111/bpa.12407. Epub 2016 Aug 2. Brain Pathol. 2017. PMID: 27338164 Free PMC article.
Faulty splicing and cytoskeleton abnormalities in Huntington's disease.
Fernández-Nogales M, Santos-Galindo M, Hernández IH, Cabrera JR, Lucas JJ. Fernández-Nogales M, et al. Among authors: lucas jj. Brain Pathol. 2016 Nov;26(6):772-778. doi: 10.1111/bpa.12430. Brain Pathol. 2016. PMID: 27529534 Free PMC article. Review.
The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease.
Hernández IH, Torres-Peraza J, Santos-Galindo M, Ramos-Morón E, Fernández-Fernández MR, Pérez-Álvarez MJ, Miranda-Vizuete A, Lucas JJ. Hernández IH, et al. Among authors: lucas jj. Acta Neuropathol. 2017 Dec;134(6):839-850. doi: 10.1007/s00401-017-1770-2. Epub 2017 Aug 31. Acta Neuropathol. 2017. PMID: 28861715 Free article.
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.
Parras A, Anta H, Santos-Galindo M, Swarup V, Elorza A, Nieto-González JL, Picó S, Hernández IH, Díaz-Hernández JI, Belloc E, Rodolosse A, Parikshak NN, Peñagarikano O, Fernández-Chacón R, Irimia M, Navarro P, Geschwind DH, Méndez R, Lucas JJ. Parras A, et al. Among authors: lucas jj. Nature. 2018 Aug;560(7719):441-446. doi: 10.1038/s41586-018-0423-5. Epub 2018 Aug 15. Nature. 2018. PMID: 30111840 Free PMC article.
Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome.
Arranz J, Balducci E, Arató K, Sánchez-Elexpuru G, Najas S, Parras A, Rebollo E, Pijuan I, Erb I, Verde G, Sahun I, Barallobre MJ, Lucas JJ, Sánchez MP, de la Luna S, Arbonés ML. Arranz J, et al. Among authors: lucas jj. Neurobiol Dis. 2019 Jul;127:210-222. doi: 10.1016/j.nbd.2019.02.022. Epub 2019 Mar 1. Neurobiol Dis. 2019. PMID: 30831192 Free PMC article.
Differential regulation of Kidins220 isoforms in Huntington's disease.
Sebastián-Serrano Á, Simón-García A, Belmonte-Alfaro A, Pose-Utrilla J, Santos-Galindo M, Del Puerto A, García-Guerra L, Hernández IH, Schiavo G, Campanero MR, Lucas JJ, Iglesias T. Sebastián-Serrano Á, et al. Among authors: lucas jj. Brain Pathol. 2020 Jan;30(1):120-136. doi: 10.1111/bpa.12761. Epub 2019 Jul 16. Brain Pathol. 2020. PMID: 31264746 Free PMC article.
281 results