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Cognitive performance in aged rats is associated with differences in distinctive neuronal populations in the ventral tegmental area and altered synaptic plasticity in the hippocampus.
Sagheddu C, Stojanovic T, Kouhnavardi S, Savchenko A, Hussein AM, Pistis M, Monje FJ, Plasenzotti R, Aufy M, Studenik CR, Lubec J, Lubec G. Sagheddu C, et al. Among authors: lubec j. Front Aging Neurosci. 2024 Feb 26;16:1357347. doi: 10.3389/fnagi.2024.1357347. eCollection 2024. Front Aging Neurosci. 2024. PMID: 38469164 Free PMC article.
Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry.
Kalaba P, Pacher K, Neill PJ, Dragacevic V, Zehl M, Wackerlig J, Kirchhofer M, Sartori SB, Gstach H, Kouhnavardi S, Fabisikova A, Pillwein M, Monje-Quiroga F, Ebner K, Prado-Roller A, Singewald N, Urban E, Langer T, Pifl C, Lubec J, Leban JJ, Lubec G. Kalaba P, et al. Among authors: lubec j. Biomolecules. 2023 Sep 19;13(9):1415. doi: 10.3390/biom13091415. Biomolecules. 2023. PMID: 37759815 Free PMC article.
The Atypical Dopamine Transporter Inhibitor CE-158 Enhances Dopamine Neurotransmission in the Prefrontal Cortex of Male Rats: A Behavioral, Electrophysiological, and Microdialysis Study.
Sagheddu C, Cancedda E, Bagheri F, Kalaba P, Muntoni AL, Lubec J, Lubec G, Sanna F, Pistis M. Sagheddu C, et al. Among authors: lubec j. Int J Neuropsychopharmacol. 2023 Nov 24;26(11):784-795. doi: 10.1093/ijnp/pyad056. Int J Neuropsychopharmacol. 2023. PMID: 37725477 Free PMC article.
Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat.
Lubec J, Hussein AM, Kalaba P, Feyissa DD, Arias-Sandoval E, Cybulska-Klosowicz A, Bezu M, Stojanovic T, Korz V, Malikovic J, Aher NY, Zehl M, Dragacevic V, Leban JJ, Sagheddu C, Wackerlig J, Pistis M, Correa M, Langer T, Urban E, Höger H, Lubec G. Lubec J, et al. Biomolecules. 2023 Mar 3;13(3):467. doi: 10.3390/biom13030467. Biomolecules. 2023. PMID: 36979402 Free PMC article.
A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions.
Kouhnavardi S, Ecevitoglu A, Dragačević V, Sanna F, Arias-Sandoval E, Kalaba P, Kirchhofer M, Lubec J, Niello M, Holy M, Zehl M, Pillwein M, Wackerlig J, Murau R, Mohrmann A, Beard KR, Sitte HH, Urban E, Sagheddu C, Pistis M, Plasenzotti R, Salamone JD, Langer T, Lubec G, Monje FJ. Kouhnavardi S, et al. Among authors: lubec j. Biomolecules. 2022 Jun 24;12(7):881. doi: 10.3390/biom12070881. Biomolecules. 2022. PMID: 35883437 Free PMC article.
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