Lu Y - Search Results

1

Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.

Yang Z, Wang JY, Yang F, Zhu KK, Wang GP, Guan Y, Ning SL, Lu Y, Li Y, Zhang C, Zheng Y, Zhou SH, Wang XW, Wang MW, Xiao P, Yi F, Zhang C, Zhang PJ, Xu F, Liu BH, Zhang H, Yu X, Gao N, Sun JP. Yang Z, et al. Among authors: lu y. Nat Chem Biol. 2024 Apr;20(4):484-492. doi: 10.1038/s41589-023-01456-6. Epub 2023 Nov 9. Nat Chem Biol. 2024. PMID: 37945893

2

Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.

Xiao P, Guo S, Wen X, He QT, Lin H, Huang SM, Gou L, Zhang C, Yang Z, Zhong YN, Yang CC, Li Y, Gong Z, Tao XN, Yang ZS, Lu Y, Li SL, He JY, Wang C, Zhang L, Kong L, Sun JP, Yu X. Xiao P, et al. Among authors: lu y. Nature. 2022 Apr;604(7907):771-778. doi: 10.1038/s41586-022-04590-8. Epub 2022 Apr 13. Nature. 2022. PMID: 35418677

3

Structural basis for the tethered peptide activation of adhesion GPCRs.

Ping YQ, Xiao P, Yang F, Zhao RJ, Guo SC, Yan X, Wu X, Zhang C, Lu Y, Zhao F, Zhou F, Xi YT, Yin W, Liu FZ, He DF, Zhang DL, Zhu ZL, Jiang Y, Du L, Feng SQ, Schöneberg T, Liebscher I, Xu HE, Sun JP. Ping YQ, et al. Among authors: lu y. Nature. 2022 Apr;604(7907):763-770. doi: 10.1038/s41586-022-04619-y. Epub 2022 Apr 13. Nature. 2022. PMID: 35418678

4

Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A_2A Receptor Targeting the Sodium Ion Pocket.

Lu Y, Liu H, Yang D, Zhong L, Xin Y, Zhao S, Wang MW, Zhou Q, Shui W. Lu Y, et al. ACS Chem Biol. 2021 Jun 18;16(6):991-1002. doi: 10.1021/acschembio.0c00899. Epub 2021 May 28. ACS Chem Biol. 2021. PMID: 34048655 Free article.

5

High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening.

Qin S, Meng M, Yang D, Bai W, Lu Y, Peng Y, Song G, Wu Y, Zhou Q, Zhao S, Huang X, McCorvy JD, Cai X, Dai A, Roth BL, Hanson MA, Liu ZJ, Wang MW, Stevens RC, Shui W. Qin S, et al. Among authors: lu y. Chem Sci. 2018 Feb 20;9(12):3192-3199. doi: 10.1039/c7sc04698g. eCollection 2018 Mar 28. Chem Sci. 2018. PMID: 29732102 Free PMC article.

6

Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor.

Lu Y, Qin S, Zhang B, Dai A, Cai X, Ma M, Gao ZG, Yang D, Stevens RC, Jacobson KA, Wang MW, Shui W. Lu Y, et al. Anal Chem. 2019 Jul 2;91(13):8162-8169. doi: 10.1021/acs.analchem.9b00477. Epub 2019 Jun 12. Anal Chem. 2019. PMID: 31094506 Free PMC article.

7

Crystal structure of misoprostol bound to the labor inducer prostaglandin E₂ receptor.

Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC. Audet M, et al. Among authors: lu y. Nat Chem Biol. 2019 Jan;15(1):11-17. doi: 10.1038/s41589-018-0160-y. Epub 2018 Dec 3. Nat Chem Biol. 2019. PMID: 30510194 Free PMC article.

8

Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E₂ receptor.

Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC. Audet M, et al. Among authors: lu y. Nat Chem Biol. 2019 Feb;15(2):206. doi: 10.1038/s41589-018-0214-1. Nat Chem Biol. 2019. PMID: 30573766

9

Structural basis for dual-mode inhibition of the ABC transporter MsbA.

Ho H, Miu A, Alexander MK, Garcia NK, Oh A, Zilberleyb I, Reichelt M, Austin CD, Tam C, Shriver S, Hu H, Labadie SS, Liang J, Wang L, Wang J, Lu Y, Purkey HE, Quinn J, Franke Y, Clark K, Beresini MH, Tan MW, Sellers BD, Maurer T, Koehler MFT, Wecksler AT, Kiefer JR, Verma V, Xu Y, Nishiyama M, Payandeh J, Koth CM. Ho H, et al. Among authors: lu y. Nature. 2018 May;557(7704):196-201. doi: 10.1038/s41586-018-0083-5. Epub 2018 May 2. Nature. 2018. PMID: 29720648

10

Correction to Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor.

Lu Y, Qin S, Zhang B, Dai A, Cai X, Ma M, Gao ZG, Yang D, Stevens RC, Jacobson KA, Wang MW, Shui W. Lu Y, et al. Anal Chem. 2020 Mar 17;92(6):4689. doi: 10.1021/acs.analchem.0c00754. Epub 2020 Mar 3. Anal Chem. 2020. PMID: 32125824 Free PMC article. No abstract available.

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