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RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis.
Guo J, Ananthakrishnan R, Qu W, Lu Y, Reiniger N, Zeng S, Ma W, Rosario R, Yan SF, Ramasamy R, D'Agati V, Schmidt AM. Guo J, et al. Among authors: lu y. J Am Soc Nephrol. 2008 May;19(5):961-72. doi: 10.1681/ASN.2007101109. Epub 2008 Feb 6. J Am Soc Nephrol. 2008. PMID: 18256352 Free PMC article.
RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy.
Wendt TM, Tanji N, Guo J, Kislinger TR, Qu W, Lu Y, Bucciarelli LG, Rong LL, Moser B, Markowitz GS, Stein G, Bierhaus A, Liliensiek B, Arnold B, Nawroth PP, Stern DM, D'Agati VD, Schmidt AM. Wendt TM, et al. Among authors: lu y. Am J Pathol. 2003 Apr;162(4):1123-37. doi: 10.1016/S0002-9440(10)63909-0. Am J Pathol. 2003. PMID: 12651605 Free PMC article.
RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB.
Cataldegirmen G, Zeng S, Feirt N, Ippagunta N, Dun H, Qu W, Lu Y, Rong LL, Hofmann MA, Kislinger T, Pachydaki SI, Jenkins DG, Weinberg A, Lefkowitch J, Rogiers X, Yan SF, Schmidt AM, Emond JC. Cataldegirmen G, et al. Among authors: lu y. J Exp Med. 2005 Feb 7;201(3):473-84. doi: 10.1084/jem.20040934. J Exp Med. 2005. PMID: 15699076 Free PMC article.
Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury.
Bucciarelli LG, Kaneko M, Ananthakrishnan R, Harja E, Lee LK, Hwang YC, Lerner S, Bakr S, Li Q, Lu Y, Song F, Qu W, Gomez T, Zou YS, Yan SF, Schmidt AM, Ramasamy R. Bucciarelli LG, et al. Among authors: lu y. Circulation. 2006 Mar 7;113(9):1226-34. doi: 10.1161/CIRCULATIONAHA.105.575993. Epub 2006 Feb 27. Circulation. 2006. PMID: 16505177
RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model.
Aleshin A, Ananthakrishnan R, Li Q, Rosario R, Lu Y, Qu W, Song F, Bakr S, Szabolcs M, D'Agati V, Liu R, Homma S, Schmidt AM, Yan SF, Ramasamy R. Aleshin A, et al. Among authors: lu y. Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1823-32. doi: 10.1152/ajpheart.01210.2007. Epub 2008 Feb 1. Am J Physiol Heart Circ Physiol. 2008. PMID: 18245563 Free article.
Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse.
Reiniger N, Lau K, McCalla D, Eby B, Cheng B, Lu Y, Qu W, Quadri N, Ananthakrishnan R, Furmansky M, Rosario R, Song F, Rai V, Weinberg A, Friedman R, Ramasamy R, D'Agati V, Schmidt AM. Reiniger N, et al. Among authors: lu y. Diabetes. 2010 Aug;59(8):2043-54. doi: 10.2337/db09-1766. Epub 2010 Jul 13. Diabetes. 2010. PMID: 20627935 Free PMC article.
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