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Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity.
Zhu Y, Ma J, Shen R, Lin J, Li S, Lu X, Stelzel JL, Kong J, Cheng L, Vuong I, Yao ZC, Wei C, Korinetz NM, Toh WH, Choy J, Reynolds RA, Shears MJ, Cho WJ, Livingston NK, Howard GP, Hu Y, Tzeng SY, Zack DJ, Green JJ, Zheng L, Doloff JC, Schneck JP, Reddy SK, Murphy SC, Mao HQ. Zhu Y, et al. Among authors: lu x. Nat Biomed Eng. 2023 Dec 11. doi: 10.1038/s41551-023-01131-0. Online ahead of print. Nat Biomed Eng. 2023. PMID: 38082180
Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors.
Abramson A, Frederiksen MR, Vegge A, Jensen B, Poulsen M, Mouridsen B, Jespersen MO, Kirk RK, Windum J, Hubálek F, Water JJ, Fels J, Gunnarsson SB, Bohr A, Straarup EM, Ley MWH, Lu X, Wainer J, Collins J, Tamang S, Ishida K, Hayward A, Herskind P, Buckley ST, Roxhed N, Langer R, Rahbek U, Traverso G. Abramson A, et al. Among authors: lu x. Nat Biotechnol. 2022 Jan;40(1):103-109. doi: 10.1038/s41587-021-01024-0. Epub 2021 Aug 30. Nat Biotechnol. 2022. PMID: 34462588 Free PMC article.
A luminal unfolding microneedle injector for oral delivery of macromolecules.
Abramson A, Caffarel-Salvador E, Soares V, Minahan D, Tian RY, Lu X, Dellal D, Gao Y, Kim S, Wainer J, Collins J, Tamang S, Hayward A, Yoshitake T, Lee HC, Fujimoto J, Fels J, Frederiksen MR, Rahbek U, Roxhed N, Langer R, Traverso G. Abramson A, et al. Among authors: lu x. Nat Med. 2019 Oct;25(10):1512-1518. doi: 10.1038/s41591-019-0598-9. Epub 2019 Oct 7. Nat Med. 2019. PMID: 31591601 Free PMC article.
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