Lu R - Search Results

1

Autophagy inhibition impairs leukemia stem cell function in FLT3-ITD AML but has antagonistic interactions with tyrosine kinase inhibition.

Qiu S, Kumar H, Yan C, Li H, Paterson AJ, Anderson NR, He J, Yang J, Xie M, Crossman DK, Lu R, Welner RS, Bhatia R. Qiu S, et al. Among authors: lu r. Leukemia. 2022 Nov;36(11):2621-2633. doi: 10.1038/s41375-022-01719-6. Epub 2022 Oct 11. Leukemia. 2022. PMID: 36220999 Free PMC article.

2

Metabolic alterations mediated by STAT3 promotes drug persistence in CML.

Patel SB, Nemkov T, Stefanoni D, Benavides GA, Bassal MA, Crown BL, Matkins VR, Camacho V, Kuznetsova V, Hoang AT, Tenen DE, Wolock SL, Park J, Ying L, Yue Z, Chen JY, Yang H, Tenen DG, Ferrell PB, Lu R, Darley-Usmar V, D'Alessandro A, Bhatia R, Welner RS. Patel SB, et al. Among authors: lu r. Leukemia. 2021 Dec;35(12):3371-3382. doi: 10.1038/s41375-021-01315-0. Epub 2021 Jun 12. Leukemia. 2021. PMID: 34120146 Free PMC article.

3

Transcription factor MEF2D is required for the maintenance of MLL-rearranged acute myeloid leukemia.

Zhao L, Zhang P, Galbo PM, Zhou X, Aryal S, Qiu S, Zhang H, Zhou Y, Li C, Zheng D, Bhatia R, Lu R. Zhao L, et al. Among authors: lu r. Blood Adv. 2021 Nov 23;5(22):4727-4740. doi: 10.1182/bloodadvances.2021004469. Blood Adv. 2021. PMID: 34597364 Free PMC article.

4

UTX loss alters therapeutic responses in KMT2A-rearranged acute myeloid leukemia.

Zhou X, Zhang P, Aryal S, Zhang L, Lu R. Zhou X, et al. Among authors: lu r. Leukemia. 2023 Jan;37(1):226-230. doi: 10.1038/s41375-022-01741-8. Epub 2022 Oct 29. Leukemia. 2023. PMID: 36309561 No abstract available.

5

Metabolic adaptation to tyrosine kinase inhibition in leukemia stem cells.

Qiu S, Sheth V, Yan C, Liu J, Chacko BK, Li H, Crossman DK, Fortmann SD, Aryal S, Rennhack A, Grant MB, Welner RS, Paterson AJ, Wende AR, Darley-Usmar VM, Lu R, Locasale JW, Bhatia R. Qiu S, et al. Among authors: lu r. Blood. 2023 Aug 10;142(6):574-588. doi: 10.1182/blood.2022018196. Blood. 2023. PMID: 37192295

6

Molecular regulators of HOXA9 in acute myeloid leukemia.

Aryal S, Zhang Y, Wren S, Li C, Lu R. Aryal S, et al. Among authors: lu r. FEBS J. 2023 Jan;290(2):321-339. doi: 10.1111/febs.16268. Epub 2021 Nov 19. FEBS J. 2023. PMID: 34743404 Free article. Review.

7

TBX20 Improves Contractility and Mitochondrial Function During Direct Human Cardiac Reprogramming.

Tang Y, Aryal S, Geng X, Zhou X, Fast VG, Zhang J, Lu R, Zhou Y. Tang Y, et al. Among authors: lu r. Circulation. 2022 Nov 15;146(20):1518-1536. doi: 10.1161/CIRCULATIONAHA.122.059713. Epub 2022 Sep 14. Circulation. 2022. PMID: 36102189 Free PMC article.

8

HOXA9/MEIS1 targets in leukemia: reinforced signaling networks and therapeutic opportunities.

Zhou X, Lu R. Zhou X, et al. Among authors: lu r. Haematologica. 2023 May 1;108(5):1205-1207. doi: 10.3324/haematol.2022.281779. Haematologica. 2023. PMID: 36005566 Free PMC article. No abstract available.

9

Inhibition of EZH2 primes the cardiac gene activation via removal of epigenetic repression during human direct cardiac reprogramming.

Tang Y, Zhao L, Yu X, Zhang J, Qian L, Jin J, Lu R, Zhou Y. Tang Y, et al. Among authors: lu r. Stem Cell Res. 2021 May;53:102365. doi: 10.1016/j.scr.2021.102365. Epub 2021 Apr 27. Stem Cell Res. 2021. PMID: 34087994 Free PMC article.

10

Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen.

Zhang H, Zhang Y, Zhou X, Wright S, Hyle J, Zhao L, An J, Zhao X, Shao Y, Xu B, Lee HM, Chen T, Zhou Y, Chen X, Lu R, Li C. Zhang H, et al. Among authors: lu r. Elife. 2020 Oct 1;9:e57858. doi: 10.7554/eLife.57858. Elife. 2020. PMID: 33001025 Free PMC article.

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