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5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals.
Sisignano M, Park CK, Angioni C, Zhang DD, von Hehn C, Cobos EJ, Ghasemlou N, Xu ZZ, Kumaran V, Lu R, Grant A, Fischer MJ, Schmidtko A, Reeh P, Ji RR, Woolf CJ, Geisslinger G, Scholich K, Brenneis C. Sisignano M, et al. Among authors: lu r. J Neurosci. 2012 May 2;32(18):6364-72. doi: 10.1523/JNEUROSCI.5793-11.2012. J Neurosci. 2012. PMID: 22553041 Free PMC article.
NADPH oxidase-4 maintains neuropathic pain after peripheral nerve injury.
Kallenborn-Gerhardt W, Schröder K, Del Turco D, Lu R, Kynast K, Kosowski J, Niederberger E, Shah AM, Brandes RP, Geisslinger G, Schmidtko A. Kallenborn-Gerhardt W, et al. Among authors: lu r. J Neurosci. 2012 Jul 25;32(30):10136-45. doi: 10.1523/JNEUROSCI.6227-11.2012. J Neurosci. 2012. PMID: 22836249 Free PMC article.
4,931 results