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Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy.
Ullah I, Prévost J, Ladinsky MS, Stone H, Lu M, Anand SP, Beaudoin-Bussières G, Symmes K, Benlarbi M, Ding S, Gasser R, Fink C, Chen Y, Tauzin A, Goyette G, Bourassa C, Medjahed H, Mack M, Chung K, Wilen CB, Dekaban GA, Dikeakos JD, Bruce EA, Kaufmann DE, Stamatatos L, McGuire AT, Richard J, Pazgier M, Bjorkman PJ, Mothes W, Finzi A, Kumar P, Uchil PD. Ullah I, et al. Among authors: lu m. Immunity. 2021 Sep 14;54(9):2143-2158.e15. doi: 10.1016/j.immuni.2021.08.015. Epub 2021 Aug 18. Immunity. 2021. PMID: 34453881 Free PMC article.
Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.
Lu M, Ma X, Castillo-Menendez LR, Gorman J, Alsahafi N, Ermel U, Terry DS, Chambers M, Peng D, Zhang B, Zhou T, Reichard N, Wang K, Grover JR, Carman BP, Gardner MR, Nikić-Spiegel I, Sugawara A, Arthos J, Lemke EA, Smith AB 3rd, Farzan M, Abrams C, Munro JB, McDermott AB, Finzi A, Kwong PD, Blanchard SC, Sodroski JG, Mothes W. Lu M, et al. Nature. 2019 Apr;568(7752):415-419. doi: 10.1038/s41586-019-1101-y. Epub 2019 Apr 10. Nature. 2019. PMID: 30971821 Free PMC article.
Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles.
Lu M, Uchil PD, Li W, Zheng D, Terry DS, Gorman J, Shi W, Zhang B, Zhou T, Ding S, Gasser R, Prevost J, Beaudoin-Bussieres G, Anand SP, Laumaea A, Grover JR, Lihong L, Ho DD, Mascola J, Finzi A, Kwong PD, Blanchard SC, Mothes W. Lu M, et al. bioRxiv [Preprint]. 2020 Sep 13:2020.09.10.286948. doi: 10.1101/2020.09.10.286948. bioRxiv. 2020. PMID: 32935100 Free PMC article. Updated. Preprint.
Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles.
Lu M, Uchil PD, Li W, Zheng D, Terry DS, Gorman J, Shi W, Zhang B, Zhou T, Ding S, Gasser R, Prévost J, Beaudoin-Bussières G, Anand SP, Laumaea A, Grover JR, Liu L, Ho DD, Mascola JR, Finzi A, Kwong PD, Blanchard SC, Mothes W. Lu M, et al. Cell Host Microbe. 2020 Dec 9;28(6):880-891.e8. doi: 10.1016/j.chom.2020.11.001. Epub 2020 Nov 13. Cell Host Microbe. 2020. PMID: 33242391 Free PMC article.
A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses.
Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. Tauzin A, et al. Among authors: lu m. bioRxiv [Preprint]. 2021 Mar 18:2021.03.18.435972. doi: 10.1101/2021.03.18.435972. bioRxiv. 2021. PMID: 33758857 Free PMC article. Preprint.
Live Imaging of SARS-CoV-2 Infection in Mice Reveals Neutralizing Antibodies Require Fc Function for Optimal Efficacy.
Ullah I, Prévost J, Ladinsky MS, Stone H, Lu M, Anand SP, Beaudoin-Bussières G, Symmes K, Benlarbi M, Ding S, Gasser R, Fink C, Chen Y, Tauzin A, Goyette G, Bourassa C, Medjahed H, Mack M, Chung K, Wilen CB, Dekaban GA, Dikeakos JD, Bruce EA, Kaufmann DE, Stamatatos L, McGuire AT, Richard J, Pazgier M, Bjorkman PJ, Mothes W, Finzi A, Kumar P, Uchil PD. Ullah I, et al. Among authors: lu m. bioRxiv [Preprint]. 2021 Jun 28:2021.03.22.436337. doi: 10.1101/2021.03.22.436337. bioRxiv. 2021. PMID: 33791699 Free PMC article. Updated. Preprint.
A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses.
Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, De Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. Tauzin A, et al. Among authors: lu m. Cell Host Microbe. 2021 Jul 14;29(7):1137-1150.e6. doi: 10.1016/j.chom.2021.06.001. Epub 2021 Jun 4. Cell Host Microbe. 2021. PMID: 34133950 Free PMC article.
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