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CDK9 inhibitors reactivate p53 by downregulating iASPP.
Wu J, Liang Y, Tan Y, Tang Y, Song H, Wang Z, Li Y, Lu M. Wu J, et al. Among authors: lu m. Cell Signal. 2020 Mar;67:109508. doi: 10.1016/j.cellsig.2019.109508. Epub 2019 Dec 19. Cell Signal. 2020. PMID: 31866490
iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition.
Chen S, Wu J, Zhong S, Li Y, Zhang P, Ma J, Ren J, Tan Y, Wang Y, Au KF, Siebold C, Bond GL, Chen Z, Lu M, Jones EY, Lu X. Chen S, et al. Among authors: lu x, lu m. Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17470-17479. doi: 10.1073/pnas.1909393116. Epub 2019 Aug 8. Proc Natl Acad Sci U S A. 2019. PMID: 31395738 Free PMC article.
Identification of proteasome and caspase inhibitors targeting SARS-CoV-2 Mpro.
Wang Z, Zhao Y, Wang Q, Xing Y, Feng L, Kong J, Peng C, Zhang L, Yang H, Lu M. Wang Z, et al. Among authors: lu m. Signal Transduct Target Ther. 2021 Jun 1;6(1):214. doi: 10.1038/s41392-021-00639-8. Signal Transduct Target Ther. 2021. PMID: 34075025 Free PMC article. No abstract available.
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