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Role of CYP2A6 in Methimazole Bioactivation and Hepatotoxicity.
Li J, Hussain Z, Zhu J, Lei S, Lu J, Ma X. Li J, et al. Among authors: lu j. Chem Res Toxicol. 2021 Dec 20;34(12):2534-2539. doi: 10.1021/acs.chemrestox.1c00300. Epub 2021 Nov 17. Chem Res Toxicol. 2021. PMID: 34788025 Free PMC article.
Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors.
Zhu J, Lei S, Lu J, Hao Y, Qian Q, Devanathan AS, Feng Z, Xie XQ, Wipf P, Ma X. Zhu J, et al. Among authors: lu j. Eur J Med Chem. 2023 Nov 5;259:115666. doi: 10.1016/j.ejmech.2023.115666. Epub 2023 Jul 20. Eur J Med Chem. 2023. PMID: 37482017
Pregnane X receptor activation potentiates ritonavir hepatotoxicity.
Shehu AI, Lu J, Wang P, Zhu J, Wang Y, Yang D, McMahon D, Xie W, Gonzalez FJ, Ma X. Shehu AI, et al. Among authors: lu j. J Clin Invest. 2019 Apr 30;129(7):2898-2903. doi: 10.1172/JCI128274. J Clin Invest. 2019. PMID: 31039134 Free PMC article.
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