Lozano G - Search Results

1

Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program.

Gencel-Augusto J, Su X, Qi Y, Whitley EM, Pant V, Xiong S, Shah V, Lin J, Perez E, Fiorotto ML, Mahmud I, Jain AK, Lorenzi PL, Navin NE, Richie ER, Lozano G. Gencel-Augusto J, et al. Among authors: lozano g. Cancer Discov. 2023 May 4;13(5):1230-1249. doi: 10.1158/2159-8290.CD-22-0872. Cancer Discov. 2023. PMID: 37067911 Free PMC article.

2

Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.

Grier JD, Xiong S, Elizondo-Fraire AC, Parant JM, Lozano G. Grier JD, et al. Among authors: lozano g. Mol Cell Biol. 2006 Jan;26(1):192-8. doi: 10.1128/MCB.26.1.192-198.2006. Mol Cell Biol. 2006. PMID: 16354690 Free PMC article.

3

Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.

Xiong S, Van Pelt CS, Elizondo-Fraire AC, Liu G, Lozano G. Xiong S, et al. Among authors: lozano g. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3226-31. doi: 10.1073/pnas.0508500103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492743 Free PMC article.

4

Loss of Mdm4 results in p53-dependent dilated cardiomyopathy.

Xiong S, Van Pelt CS, Elizondo-Fraire AC, Fernandez-Garcia B, Lozano G. Xiong S, et al. Among authors: lozano g. Circulation. 2007 Jun 12;115(23):2925-30. doi: 10.1161/CIRCULATIONAHA.107.689901. Epub 2007 May 28. Circulation. 2007. PMID: 17533180

5

EWS-FLI1 induces developmental abnormalities and accelerates sarcoma formation in a transgenic mouse model.

Lin PP, Pandey MK, Jin F, Xiong S, Deavers M, Parant JM, Lozano G. Lin PP, et al. Among authors: lozano g. Cancer Res. 2008 Nov 1;68(21):8968-75. doi: 10.1158/0008-5472.CAN-08-0573. Cancer Res. 2008. PMID: 18974141 Free PMC article.

6

Spontaneous tumorigenesis in mice overexpressing the p53-negative regulator Mdm4.

Xiong S, Pant V, Suh YA, Van Pelt CS, Wang Y, Valentin-Vega YA, Post SM, Lozano G. Xiong S, et al. Among authors: lozano g. Cancer Res. 2010 Sep 15;70(18):7148-54. doi: 10.1158/0008-5472.CAN-10-1457. Epub 2010 Aug 24. Cancer Res. 2010. PMID: 20736370 Free PMC article.

7

A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development.

Post SM, Quintás-Cardama A, Pant V, Iwakuma T, Hamir A, Jackson JG, Maccio DR, Bond GL, Johnson DG, Levine AJ, Lozano G. Post SM, et al. Among authors: lozano g. Cancer Cell. 2010 Sep 14;18(3):220-30. doi: 10.1016/j.ccr.2010.07.010. Cancer Cell. 2010. PMID: 20832750 Free PMC article.

8

Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation.

Wang Y, Suh YA, Fuller MY, Jackson JG, Xiong S, Terzian T, Quintás-Cardama A, Bankson JA, El-Naggar AK, Lozano G. Wang Y, et al. Among authors: lozano g. J Clin Invest. 2011 Mar;121(3):893-904. doi: 10.1172/JCI44504. J Clin Invest. 2011. PMID: 21285512 Free PMC article.

9

Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.

Pant V, Xiong S, Iwakuma T, Quintás-Cardama A, Lozano G. Pant V, et al. Among authors: lozano g. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11995-2000. doi: 10.1073/pnas.1102241108. Epub 2011 Jul 5. Proc Natl Acad Sci U S A. 2011. PMID: 21730132 Free PMC article.

10

The ups and downs of p53 regulation in hematopoietic stem cells.

Abbas HA, Pant V, Lozano G. Abbas HA, et al. Among authors: lozano g. Cell Cycle. 2011 Oct 1;10(19):3257-62. doi: 10.4161/cc.10.19.17721. Epub 2011 Oct 1. Cell Cycle. 2011. PMID: 21957490 Free PMC article.

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