Lozach O - Search Results

1

Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors.

Labrière C, Lozach O, Blairvacq M, Meijer L, Guillou C. Labrière C, et al. Among authors: lozach o. Eur J Med Chem. 2016 Nov 29;124:920-934. doi: 10.1016/j.ejmech.2016.08.069. Epub 2016 Aug 31. Eur J Med Chem. 2016. PMID: 27676471

2

Thiazolo[5,4-f]quinazolin-9-ones, inhibitors of glycogen synthase kinase-3.

Testard A, Logé C, Léger B, Robert JM, Lozach O, Blairvacq M, Meijer L, Thiéry V, Besson T. Testard A, et al. Among authors: lozach o. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3419-23. doi: 10.1016/j.bmcl.2006.04.006. Epub 2006 Apr 27. Bioorg Med Chem Lett. 2006. PMID: 16644220

3

Synthesis of novel 5-substituted indirubins as protein kinases inhibitors.

Beauchard A, Ferandin Y, Frère S, Lozach O, Blairvacq M, Meijer L, Thiéry V, Besson T. Beauchard A, et al. Among authors: lozach o. Bioorg Med Chem. 2006 Sep 15;14(18):6434-43. doi: 10.1016/j.bmc.2006.05.036. Epub 2006 Jun 8. Bioorg Med Chem. 2006. PMID: 16759872

4

Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents.

Kassis P, Brzeszcz J, Bénéteau V, Lozach O, Meijer L, Le Guével R, Guillouzo C, Lewiński K, Bourg S, Colliandre L, Routier S, Mérour JY. Kassis P, et al. Among authors: lozach o. Eur J Med Chem. 2011 Nov;46(11):5416-34. doi: 10.1016/j.ejmech.2011.08.048. Epub 2011 Sep 8. Eur J Med Chem. 2011. PMID: 21944287

5

Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases.

Nguyen TB, Lozach O, Surpateanu G, Wang Q, Retailleau P, Iorga BI, Meijer L, Guéritte F. Nguyen TB, et al. Among authors: lozach o. J Med Chem. 2012 Mar 22;55(6):2811-9. doi: 10.1021/jm201727w. Epub 2012 Mar 1. J Med Chem. 2012. PMID: 22352892

6

Synthesis and biological evaluation of N-arylbenzo[b]thieno[3,2-d]pyrimidin-4-amines and their pyrido and pyrazino analogues as Ser/Thr kinase inhibitors.

Loidreau Y, Marchand P, Dubouilh-Benard C, Nourrisson MR, Duflos M, Lozach O, Loaëc N, Meijer L, Besson T. Loidreau Y, et al. Among authors: lozach o. Eur J Med Chem. 2012 Dec;58:171-83. doi: 10.1016/j.ejmech.2012.10.006. Epub 2012 Oct 16. Eur J Med Chem. 2012. PMID: 23124214

7

Synthesis, biological evaluation and molecular modelling studies of 4-anilinoquinazoline derivatives as protein kinase inhibitors.

Waiker DK, Karthikeyan C, Poongavanam V, Kongsted J, Lozach O, Meijer L, Trivedi P. Waiker DK, et al. Among authors: lozach o. Bioorg Med Chem. 2014 Mar 15;22(6):1909-15. doi: 10.1016/j.bmc.2014.01.044. Epub 2014 Jan 31. Bioorg Med Chem. 2014. PMID: 24530227

8

Synthesis and optimization of an original V-shaped collection of 4-7-disubstituted pyrido[3,2-d]pyrimidines as CDK5 and DYRK1A inhibitors.

Dehbi O, Tikad A, Bourg S, Bonnet P, Lozach O, Meijer L, Aadil M, Akssira M, Guillaumet G, Routier S. Dehbi O, et al. Among authors: lozach o. Eur J Med Chem. 2014 Jun 10;80:352-63. doi: 10.1016/j.ejmech.2014.04.055. Epub 2014 Apr 22. Eur J Med Chem. 2014. PMID: 24793883

9

Synthesis and biological evaluation of tetrahydro[1,4]diazepino[1,2-a]indol-1-ones as cyclin-dependent kinase inhibitors.

Putey A, Fournet G, Lozach O, Perrin L, Meijer L, Joseph B. Putey A, et al. Among authors: lozach o. Eur J Med Chem. 2014 Aug 18;83:617-29. doi: 10.1016/j.ejmech.2014.06.063. Epub 2014 Jun 28. Eur J Med Chem. 2014. PMID: 24998602

10

10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.

Falke H, Chaikuad A, Becker A, Loaëc N, Lozach O, Abu Jhaisha S, Becker W, Jones PG, Preu L, Baumann K, Knapp S, Meijer L, Kunick C. Falke H, et al. Among authors: lozach o. J Med Chem. 2015 Apr 9;58(7):3131-43. doi: 10.1021/jm501994d. Epub 2015 Mar 23. J Med Chem. 2015. PMID: 25730262 Free PMC article.

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