Loza MI - Search Results

1

3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A_2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition.

Majellaro M, Jespers W, Crespo A, Núñez MJ, Novio S, Azuaje J, Prieto-Díaz R, Gioé C, Alispahic B, Brea J, Loza MI, Freire-Garabal M, Garcia-Santiago C, Rodríguez-García C, García-Mera X, Caamaño O, Fernandez-Masaguer C, Sardina JF, Stefanachi A, El Maatougui A, Mallo-Abreu A, Åqvist J, Gutiérrez-de-Terán H, Sotelo E. Majellaro M, et al. Among authors: loza mi. J Med Chem. 2021 Jan 14;64(1):458-480. doi: 10.1021/acs.jmedchem.0c01431. Epub 2020 Dec 29. J Med Chem. 2021. PMID: 33372800

2

Chemoenzymatic synthesis and binding affinity of novel (R)- and (S)-3-aminomethyl-1-tetralones, potential atypical antipsychotics.

Caro Y, Torrado M, Masaguer CF, Raviña E, Padín F, Brea J, Loza MI. Caro Y, et al. Among authors: loza mi. Bioorg Med Chem Lett. 2004 Feb 9;14(3):585-9. doi: 10.1016/j.bmcl.2003.11.064. Bioorg Med Chem Lett. 2004. PMID: 14741248

3

Synthesis and binding affinity of novel 3-aminoethyl-1-tetralones, potential atypical antipsychotics.

Alvarado M, Coelho A, Masaguer CF, Raviña E, Brea J, Padín JF, Loza MI. Alvarado M, et al. Among authors: loza mi. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3063-6. doi: 10.1016/j.bmcl.2005.04.022. Bioorg Med Chem Lett. 2005. PMID: 15878662

4

Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics.

Barceló M, Raviña E, Masaguer CF, Domínguez E, Areias FM, Brea J, Loza MI. Barceló M, et al. Among authors: loza mi. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4873-7. doi: 10.1016/j.bmcl.2007.06.045. Epub 2007 Jun 14. Bioorg Med Chem Lett. 2007. PMID: 17588750

5

Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics.

Aranda R, Villalba K, Raviña E, Masaguer CF, Brea J, Areias F, Domínguez E, Selent J, López L, Sanz F, Pastor M, Loza MI. Aranda R, et al. Among authors: loza mi. J Med Chem. 2008 Oct 9;51(19):6085-94. doi: 10.1021/jm800602w. Epub 2008 Sep 11. J Med Chem. 2008. PMID: 18783204

6

Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands.

Ortega R, Raviña E, Masaguer CF, Areias F, Brea J, Loza MI, López L, Selent J, Pastor M, Sanz F. Ortega R, et al. Among authors: loza mi. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1773-8. doi: 10.1016/j.bmcl.2009.01.067. Epub 2009 Jan 27. Bioorg Med Chem Lett. 2009. PMID: 19217777

7

Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif.

Carro L, Raviña E, Domínguez E, Brea J, Loza MI, Masaguer CF. Carro L, et al. Among authors: loza mi. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6059-62. doi: 10.1016/j.bmcl.2009.09.041. Epub 2009 Sep 17. Bioorg Med Chem Lett. 2009. PMID: 19796944

8

In silico directed chemical probing of the adenosine receptor family.

Areias FM, Brea J, Gregori-Puigjané E, Zaki ME, Carvalho MA, Domínguez E, Gutiérrez-de-Terán H, Proença MF, Loza MI, Mestres J. Areias FM, et al. Among authors: loza mi. Bioorg Med Chem. 2010 May 1;18(9):3043-52. doi: 10.1016/j.bmc.2010.03.048. Epub 2010 Mar 27. Bioorg Med Chem. 2010. PMID: 20382540

9

Synthesis of novel chromene scaffolds for adenosine receptors.

Costa M, Areias F, Castro M, Brea J, Loza MI, Proença F. Costa M, et al. Among authors: loza mi. Org Biomol Chem. 2011 Jun 7;9(11):4242-9. doi: 10.1039/c1ob05305a. Epub 2011 Apr 20. Org Biomol Chem. 2011. PMID: 21509353

10

Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model.

Redondo M, Zarruk JG, Ceballos P, Pérez DI, Pérez C, Perez-Castillo A, Moro MA, Brea J, Val C, Cadavid MI, Loza MI, Campillo NE, Martínez A, Gil C. Redondo M, et al. Among authors: loza mi. Eur J Med Chem. 2012 Jan;47(1):175-85. doi: 10.1016/j.ejmech.2011.10.040. Epub 2011 Nov 4. Eur J Med Chem. 2012. PMID: 22100138

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