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Alveolar Differentiation Drives Resistance to KRAS Inhibition in Lung Adenocarcinoma.
Li Z, Zhuang X, Pan CH, Yan Y, Thummalapalli R, Hallin J, Torborg S, Singhal A, Chang JC, Manchado E, Dow LE, Yaeger R, Christensen JG, Lowe SW, Rudin CM, Joost S, Tammela T. Li Z, et al. Among authors: lowe sw. Cancer Discov. 2024 Feb 8;14(2):308-325. doi: 10.1158/2159-8290.CD-23-0289. Cancer Discov. 2024. PMID: 37931288
A modular and flexible ESC-based mouse model of pancreatic cancer.
Saborowski M, Saborowski A, Morris JP 4th, Bosbach B, Dow LE, Pelletier J, Klimstra DS, Lowe SW. Saborowski M, et al. Among authors: lowe sw. Genes Dev. 2014 Jan 1;28(1):85-97. doi: 10.1101/gad.232082.113. Genes Dev. 2014. PMID: 24395249 Free PMC article.
Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling.
Weissmueller S, Manchado E, Saborowski M, Morris JP 4th, Wagenblast E, Davis CA, Moon SH, Pfister NT, Tschaharganeh DF, Kitzing T, Aust D, Markert EK, Wu J, Grimmond SM, Pilarsky C, Prives C, Biankin AV, Lowe SW. Weissmueller S, et al. Among authors: lowe sw. Cell. 2014 Apr 10;157(2):382-394. doi: 10.1016/j.cell.2014.01.066. Cell. 2014. PMID: 24725405 Free PMC article.
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.
Tschaharganeh DF, Xue W, Calvisi DF, Evert M, Michurina TV, Dow LE, Banito A, Katz SF, Kastenhuber ER, Weissmueller S, Huang CH, Lechel A, Andersen JB, Capper D, Zender L, Longerich T, Enikolopov G, Lowe SW. Tschaharganeh DF, et al. Among authors: lowe sw. Cell. 2014 Jul 31;158(3):579-92. doi: 10.1016/j.cell.2014.05.051. Cell. 2014. PMID: 25083869 Free PMC article.
Development of siRNA payloads to target KRAS-mutant cancer.
Yuan TL, Fellmann C, Lee CS, Ritchie CD, Thapar V, Lee LC, Hsu DJ, Grace D, Carver JO, Zuber J, Luo J, McCormick F, Lowe SW. Yuan TL, et al. Among authors: lowe sw. Cancer Discov. 2014 Oct;4(10):1182-1197. doi: 10.1158/2159-8290.CD-13-0900. Epub 2014 Aug 6. Cancer Discov. 2014. PMID: 25100204 Free PMC article.
354 results