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Oncogenic ras and p53 cooperate to induce cellular senescence.
Ferbeyre G, de Stanchina E, Lin AW, Querido E, McCurrach ME, Hannon GJ, Lowe SW. Ferbeyre G, et al. Among authors: lowe sw. Mol Cell Biol. 2002 May;22(10):3497-508. doi: 10.1128/MCB.22.10.3497-3508.2002. Mol Cell Biol. 2002. PMID: 11971980 Free PMC article.
Suppression of tumorigenesis by the p53 target PUMA.
Hemann MT, Zilfou JT, Zhao Z, Burgess DJ, Hannon GJ, Lowe SW. Hemann MT, et al. Among authors: lowe sw. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9333-8. doi: 10.1073/pnas.0403286101. Epub 2004 Jun 10. Proc Natl Acad Sci U S A. 2004. PMID: 15192153 Free PMC article.
Loss of p53 impedes the antileukemic response to BCR-ABL inhibition.
Wendel HG, de Stanchina E, Cepero E, Ray S, Emig M, Fridman JS, Veach DR, Bornmann WG, Clarkson B, McCombie WR, Kogan SC, Hochhaus A, Lowe SW. Wendel HG, et al. Among authors: lowe sw. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7444-9. doi: 10.1073/pnas.0602402103. Epub 2006 May 1. Proc Natl Acad Sci U S A. 2006. PMID: 16651519 Free PMC article.
Role of the chromobox protein CBX7 in lymphomagenesis.
Scott CL, Gil J, Hernando E, Teruya-Feldstein J, Narita M, Martínez D, Visakorpi T, Mu D, Cordon-Cardo C, Peters G, Beach D, Lowe SW. Scott CL, et al. Among authors: lowe sw. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5389-94. doi: 10.1073/pnas.0608721104. Epub 2007 Mar 20. Proc Natl Acad Sci U S A. 2007. PMID: 17374722 Free PMC article.
ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence.
Ha L, Ichikawa T, Anver M, Dickins R, Lowe S, Sharpless NE, Krimpenfort P, Depinho RA, Bennett DC, Sviderskaya EV, Merlino G. Ha L, et al. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):10968-73. doi: 10.1073/pnas.0611638104. Epub 2007 Jun 19. Proc Natl Acad Sci U S A. 2007. PMID: 17576930 Free PMC article.
Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc.
Tworkowski KA, Chakraborty AA, Samuelson AV, Seger YR, Narita M, Hannon GJ, Lowe SW, Tansey WP. Tworkowski KA, et al. Among authors: lowe sw. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6103-8. doi: 10.1073/pnas.0802095105. Epub 2008 Apr 14. Proc Natl Acad Sci U S A. 2008. PMID: 18413597 Free PMC article.
Topoisomerase levels determine chemotherapy response in vitro and in vivo.
Burgess DJ, Doles J, Zender L, Xue W, Ma B, McCombie WR, Hannon GJ, Lowe SW, Hemann MT. Burgess DJ, et al. Among authors: lowe sw. Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9053-8. doi: 10.1073/pnas.0803513105. Epub 2008 Jun 23. Proc Natl Acad Sci U S A. 2008. PMID: 18574145 Free PMC article.
370 results