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p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression.
Moon SH, Huang CH, Houlihan SL, Regunath K, Freed-Pastor WA, Morris JP 4th, Tschaharganeh DF, Kastenhuber ER, Barsotti AM, Culp-Hill R, Xue W, Ho YJ, Baslan T, Li X, Mayle A, de Stanchina E, Zender L, Tong DR, D'Alessandro A, Lowe SW, Prives C. Moon SH, et al. Among authors: lowe sw. Cell. 2019 Jan 24;176(3):564-580.e19. doi: 10.1016/j.cell.2018.11.011. Epub 2018 Dec 20. Cell. 2019. PMID: 30580964 Free PMC article.
Cancer therapy and p53.
Lowe SW. Lowe SW. Curr Opin Oncol. 1995 Nov;7(6):547-53. doi: 10.1097/00001622-199511000-00013. Curr Opin Oncol. 1995. PMID: 8547404 Review.
E1A signaling to p53 involves the p19(ARF) tumor suppressor.
de Stanchina E, McCurrach ME, Zindy F, Shieh SY, Ferbeyre G, Samuelson AV, Prives C, Roussel MF, Sherr CJ, Lowe SW. de Stanchina E, et al. Among authors: lowe sw. Genes Dev. 1998 Aug 1;12(15):2434-42. doi: 10.1101/gad.12.15.2434. Genes Dev. 1998. PMID: 9694807 Free PMC article.
Oncogenic ras and p53 cooperate to induce cellular senescence.
Ferbeyre G, de Stanchina E, Lin AW, Querido E, McCurrach ME, Hannon GJ, Lowe SW. Ferbeyre G, et al. Among authors: lowe sw. Mol Cell Biol. 2002 May;22(10):3497-508. doi: 10.1128/MCB.22.10.3497-3508.2002. Mol Cell Biol. 2002. PMID: 11971980 Free PMC article.
Dissecting p53 tumor suppressor functions in vivo.
Schmitt CA, Fridman JS, Yang M, Baranov E, Hoffman RM, Lowe SW. Schmitt CA, et al. Among authors: lowe sw. Cancer Cell. 2002 Apr;1(3):289-98. doi: 10.1016/s1535-6108(02)00047-8. Cancer Cell. 2002. PMID: 12086865 Free article.
Direct coupling of the cell cycle and cell death machinery by E2F.
Nahle Z, Polakoff J, Davuluri RV, McCurrach ME, Jacobson MD, Narita M, Zhang MQ, Lazebnik Y, Bar-Sagi D, Lowe SW. Nahle Z, et al. Among authors: lowe sw. Nat Cell Biol. 2002 Nov;4(11):859-64. doi: 10.1038/ncb868. Nat Cell Biol. 2002. PMID: 12389032
Tumour suppression: something for nothing?
de Stanchina E, Lowe SW. de Stanchina E, et al. Among authors: lowe sw. Nat Cell Biol. 2002 Dec;4(12):E275-6. doi: 10.1038/ncb1202-e275. Nat Cell Biol. 2002. PMID: 12461528 No abstract available.
370 results