Lowe R - Search Results

1

DNA methylation aging clocks: challenges and recommendations.

Bell CG, Lowe R, Adams PD, Baccarelli AA, Beck S, Bell JT, Christensen BC, Gladyshev VN, Heijmans BT, Horvath S, Ideker T, Issa JJ, Kelsey KT, Marioni RE, Reik W, Relton CL, Schalkwyk LC, Teschendorff AE, Wagner W, Zhang K, Rakyan VK. Bell CG, et al. Among authors: lowe r. Genome Biol. 2019 Nov 25;20(1):249. doi: 10.1186/s13059-019-1824-y. Genome Biol. 2019. PMID: 31767039 Free PMC article. Review.

2

Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species.

Lowe R, Barton C, Jenkins CA, Ernst C, Forman O, Fernandez-Twinn DS, Bock C, Rossiter SJ, Faulkes CG, Ozanne SE, Walter L, Odom DT, Mellersh C, Rakyan VK. Lowe R, et al. Genome Biol. 2018 Feb 16;19(1):22. doi: 10.1186/s13059-018-1397-1. Genome Biol. 2018. PMID: 29452591 Free PMC article.

3

Marmal-aid--a database for Infinium HumanMethylation450.

Lowe R, Rakyan VK. Lowe R, et al. BMC Bioinformatics. 2013 Dec 12;14:359. doi: 10.1186/1471-2105-14-359. BMC Bioinformatics. 2013. PMID: 24330312 Free PMC article.

4

Correcting for cell-type composition bias in epigenome-wide association studies.

Lowe R, Rakyan VK. Lowe R, et al. Genome Med. 2014 Mar 25;6(3):23. doi: 10.1186/gm540. eCollection 2014. Genome Med. 2014. PMID: 25031617 Free PMC article.

5

Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates.

Hillman SL, Finer S, Smart MC, Mathews C, Lowe R, Rakyan VK, Hitman GA, Williams DJ. Hillman SL, et al. Among authors: lowe r. Epigenetics. 2015;10(1):50-61. doi: 10.4161/15592294.2014.989741. Epub 2015 Jan 23. Epigenetics. 2015. PMID: 25496377 Free PMC article.

6

The human blood DNA methylome displays a highly distinctive profile compared with other somatic tissues.

Lowe R, Slodkowicz G, Goldman N, Rakyan VK. Lowe R, et al. Epigenetics. 2015;10(4):274-81. doi: 10.1080/15592294.2014.1003744. Epigenetics. 2015. PMID: 25634226 Free PMC article.

7

The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans.

Lowe R, Overhoff MG, Ramagopalan SV, Garbe JC, Koh J, Stampfer MR, Beach DH, Rakyan VK, Bishop CL. Lowe R, et al. Genome Biol. 2015 Sep 17;16(1):194. doi: 10.1186/s13059-015-0748-4. Genome Biol. 2015. PMID: 26381124 Free PMC article.

8

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci.

Thurner M, van de Bunt M, Torres JM, Mahajan A, Nylander V, Bennett AJ, Gaulton KJ, Barrett A, Burrows C, Bell CG, Lowe R, Beck S, Rakyan VK, Gloyn AL, McCarthy MI. Thurner M, et al. Among authors: lowe r. Elife. 2018 Feb 7;7:e31977. doi: 10.7554/eLife.31977. Elife. 2018. PMID: 29412141 Free PMC article.

9

Early life diet conditions the molecular response to post-weaning protein restriction in the mouse.

Danson AF, Marzi SJ, Lowe R, Holland ML, Rakyan VK. Danson AF, et al. Among authors: lowe r. BMC Biol. 2018 May 2;16(1):51. doi: 10.1186/s12915-018-0516-5. BMC Biol. 2018. PMID: 29720174 Free PMC article.

10

DNA methylation clocks as a predictor for ageing and age estimation in naked mole-rats, Heterocephalus glaber.

Lowe R, Danson AF, Rakyan VK, Yildizoglu S, Saldmann F, Viltard M, Friedlander G, Faulkes CG. Lowe R, et al. Aging (Albany NY). 2020 Mar 3;12(5):4394-4406. doi: 10.18632/aging.102892. Epub 2020 Mar 3. Aging (Albany NY). 2020. PMID: 32126024 Free PMC article.

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