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Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria.
Odera DO, Tuju J, Mwai K, Nkumama IN, Fürle K, Chege T, Kimathi R, Diehl S, Musasia FK, Rosenkranz M, Njuguna P, Hamaluba M, Kapulu MC, Frank R; CHMI-SIKA Study Team; Osier FHA, Abdi AI, Chi PC, de Laurent Z, Jao I, Kamuya D, Kamuyu G, Makale J, Murungi L, Musyoki J, Muthui M, Mwacharo J, Kariuki S, Mwanga D, Mwongeli J, Ndungu F, Njue M, Nyangweso G, Kimani D, Ngoi JM, Musembi J, Ngoto O, Otieno E, Ooko M, Shangala J, Wambua J, Mohammed KS, Omuoyo D, Mosobo M, Kibinge N, Kinyanjui S, Bejon P, Lowe B, Marsh K, Marsh V, Abebe Y, Billingsley PF, Sim BKL, Hoffman SL, James ER, Richie TL, Audi A, Olewe F, Oloo J, Ongecha J, Ongas MO, Koskei N, Bull PC, Hodgson SH, Kivisi C, Imwong M, Murphy SC, Ogutu B, Tarning J, Winterberg M, Williams TN. Odera DO, et al. Among authors: lowe b. Sci Transl Med. 2023 Feb 8;15(682):eabn5993. doi: 10.1126/scitranslmed.abn5993. Epub 2023 Feb 8. Sci Transl Med. 2023. PMID: 36753561
Breadth of Antibodies to Plasmodium falciparum Variant Surface Antigens Is Associated With Immunity in a Controlled Human Malaria Infection Study.
Kimingi HW, Kinyua AW, Achieng NA, Wambui KM, Mwangi S, Nguti R, Kivisi CA, Jensen ATR, Bejon P, Kapulu MC, Abdi AI, Kinyanjui SM; CHMI-SIKA Study Team. Kimingi HW, et al. Front Immunol. 2022 May 30;13:894770. doi: 10.3389/fimmu.2022.894770. eCollection 2022. Front Immunol. 2022. PMID: 35711446 Free PMC article.
All four species of human malaria parasites form rosettes.
Lowe BS, Mosobo M, Bull PC. Lowe BS, et al. Trans R Soc Trop Med Hyg. 1998 Sep-Oct;92(5):526. doi: 10.1016/s0035-9203(98)90901-4. Trans R Soc Trop Med Hyg. 1998. PMID: 9861369 No abstract available.
Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria.
Osier FH, Fegan G, Polley SD, Murungi L, Verra F, Tetteh KK, Lowe B, Mwangi T, Bull PC, Thomas AW, Cavanagh DR, McBride JS, Lanar DE, Mackinnon MJ, Conway DJ, Marsh K. Osier FH, et al. Among authors: lowe b. Infect Immun. 2008 May;76(5):2240-8. doi: 10.1128/IAI.01585-07. Epub 2008 Mar 3. Infect Immun. 2008. PMID: 18316390 Free PMC article.
Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection.
Hodgson SH, Juma E, Salim A, Magiri C, Kimani D, Njenga D, Muia A, Cole AO, Ogwang C, Awuondo K, Lowe B, Munene M, Billingsley PF, James ER, Gunasekera A, Sim BK, Njuguna P, Rampling TW, Richman A, Abebe Y, Kamuyu G, Muthui M, Elias SC, Molyneux S, Gerry S, Macharia A, Williams TN, Bull PC, Hill AV, Osier FH, Draper SJ, Bejon P, Hoffman SL, Ogutu B, Marsh K. Hodgson SH, et al. Among authors: lowe b. Front Microbiol. 2014 Dec 12;5:686. doi: 10.3389/fmicb.2014.00686. eCollection 2014. Front Microbiol. 2014. PMID: 25566206 Free PMC article.
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