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Page 1
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Björkqvist M, Wild EJ, Thiele J, Silvestroni A, Andre R, Lahiri N, Raibon E, Lee RV, Benn CL, Soulet D, Magnusson A, Woodman B, Landles C, Pouladi MA, Hayden MR, Khalili-Shirazi A, Lowdell MW, Brundin P, Bates GP, Leavitt BR, Möller T, Tabrizi SJ. Björkqvist M, et al. Among authors: lowdell mw. J Exp Med. 2008 Aug 4;205(8):1869-77. doi: 10.1084/jem.20080178. Epub 2008 Jul 14. J Exp Med. 2008. PMID: 18625748 Free PMC article.
JAK/STAT Signalling in Huntington's Disease Immune Cells.
Träger U, Magnusson A, Lahiri Swales N, Wild E, North J, Lowdell M, Björkqvist M. Träger U, et al. PLoS Curr. 2013 Dec 13;5:ecurrents.hd.5791c897b5c3bebeed93b1d1da0c0648. doi: 10.1371/currents.hd.5791c897b5c3bebeed93b1d1da0c0648. PLoS Curr. 2013. PMID: 24459609 Free PMC article.
HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation.
Träger U, Andre R, Lahiri N, Magnusson-Lind A, Weiss A, Grueninger S, McKinnon C, Sirinathsinghji E, Kahlon S, Pfister EL, Moser R, Hummerich H, Antoniou M, Bates GP, Luthi-Carter R, Lowdell MW, Björkqvist M, Ostroff GR, Aronin N, Tabrizi SJ. Träger U, et al. Among authors: lowdell mw. Brain. 2014 Mar;137(Pt 3):819-33. doi: 10.1093/brain/awt355. Epub 2014 Jan 22. Brain. 2014. PMID: 24459107 Free PMC article.
2-Phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells.
Steele AJ, Prentice AG, Hoffbrand AV, Yogashangary BC, Hart SM, Lowdell MW, Samuel ER, North JM, Nacheva EP, Chanalaris A, Kottaridis P, Cwynarski K, Wickremasinghe RG. Steele AJ, et al. Among authors: lowdell mw. Blood. 2009 Aug 6;114(6):1217-25. doi: 10.1182/blood-2008-11-190587. Epub 2009 Jun 10. Blood. 2009. PMID: 19515722 Free article.
Immunomodulatory effect of a decellularized skeletal muscle scaffold in a discordant xenotransplantation model.
Fishman JM, Lowdell MW, Urbani L, Ansari T, Burns AJ, Turmaine M, North J, Sibbons P, Seifalian AM, Wood KJ, Birchall MA, De Coppi P. Fishman JM, et al. Among authors: lowdell mw. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14360-5. doi: 10.1073/pnas.1213228110. Epub 2013 Aug 12. Proc Natl Acad Sci U S A. 2013. PMID: 23940349 Free PMC article.
147 results