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Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell. 2021 Sep 2;184(18):4651-4668.e25. doi: 10.1016/j.cell.2021.08.002. Epub 2021 Aug 26.
Cell. 2021.
PMID: 34450028
Free PMC article.
Engineered IL-21 Cytokine Muteins Fused to Anti-PD-1 Antibodies Can Improve CD8+ T Cell Function and Anti-tumor Immunity.
Shen S, Sckisel G, Sahoo A, Lalani A, Otter DD, Pearson J, DeVoss J, Cheng J, Casey SC, Case R, Yang M, Low R, Daris M, Fan B, Agrawal NJ, Ali K.
Shen S, et al.
Front Immunol. 2020 May 8;11:832. doi: 10.3389/fimmu.2020.00832. eCollection 2020.
Front Immunol. 2020.
PMID: 32457754
Free PMC article.
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