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An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma.
Davalos V, Lovell CD, Von Itter R, Dolgalev I, Agrawal P, Baptiste G, Kahler DJ, Sokolova E, Moran S, Piqué L, Vega-Saenz de Miera E, Fontanals-Cirera B, Karz A, Tsirigos A, Yun C, Darvishian F, Etchevers HC, Osman I, Esteller M, Schober M, Hernando E. Davalos V, et al. Among authors: lovell cd. Nat Commun. 2023 Apr 4;14(1):1867. doi: 10.1038/s41467-023-36967-2. Nat Commun. 2023. PMID: 37015919 Free PMC article.
The conneXion between sex and immune responses.
Forsyth KS, Jiwrajka N, Lovell CD, Toothacre NE, Anguera MC. Forsyth KS, et al. Among authors: lovell cd. Nat Rev Immunol. 2024 Feb 21. doi: 10.1038/s41577-024-00996-9. Online ahead of print. Nat Rev Immunol. 2024. PMID: 38383754 Review.
Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation.
Trefely S, Huber K, Liu J, Noji M, Stransky S, Singh J, Doan MT, Lovell CD, von Krusenstiern E, Jiang H, Bostwick A, Pepper HL, Izzo L, Zhao S, Xu JP, Bedi KC Jr, Rame JE, Bogner-Strauss JG, Mesaros C, Sidoli S, Wellen KE, Snyder NW. Trefely S, et al. Among authors: lovell cd. Mol Cell. 2022 Jan 20;82(2):447-462.e6. doi: 10.1016/j.molcel.2021.11.006. Epub 2021 Dec 1. Mol Cell. 2022. PMID: 34856123 Free PMC article.
Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes.
Di Micco R, Fontanals-Cirera B, Low V, Ntziachristos P, Yuen SK, Lovell CD, Dolgalev I, Yonekubo Y, Zhang G, Rusinova E, Gerona-Navarro G, Cañamero M, Ohlmeyer M, Aifantis I, Zhou MM, Tsirigos A, Hernando E. Di Micco R, et al. Among authors: lovell cd. Cell Rep. 2014 Oct 9;9(1):234-247. doi: 10.1016/j.celrep.2014.08.055. Epub 2014 Sep 26. Cell Rep. 2014. PMID: 25263550 Free PMC article.