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Development of a sensitive HPLC method to measure in vitro permeability of E- and Z-isomeric forms of thiosemicarbazones in Caco-2 monolayers.
Debebe Z, Nekhai S, Ashenafi M, Lovejoy DB, Kalinowski DS, Gordeuk VR, Byrnes WM, Richardson DR, Karla PK. Debebe Z, et al. Among authors: lovejoy db. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Oct 1;906:25-32. doi: 10.1016/j.jchromb.2012.08.011. Epub 2012 Aug 15. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22954966 Free PMC article.
Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9.
Debebe Z, Ammosova T, Breuer D, Lovejoy DB, Kalinowski DS, Kumar K, Jerebtsova M, Ray P, Kashanchi F, Gordeuk VR, Richardson DR, Nekhai S. Debebe Z, et al. Among authors: lovejoy db. Mol Pharmacol. 2011 Jan;79(1):185-96. doi: 10.1124/mol.110.069062. Epub 2010 Oct 18. Mol Pharmacol. 2011. PMID: 20956357 Free PMC article.
HPLC methods for determination of two novel thiosemicarbazone anti-cancer drugs (N4mT and Dp44mT) in plasma and their application to in vitro plasma stability of these agents.
Stariat J, Kovaríková P, Klimes J, Lovejoy DB, Kalinowski DS, Richardson DR. Stariat J, et al. Among authors: lovejoy db. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jan 15;877(3):316-22. doi: 10.1016/j.jchromb.2008.11.044. Epub 2008 Dec 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19097949
Anti-plasmodial activity of aroylhydrazone and thiosemicarbazone iron chelators: effect on erythrocyte membrane integrity, parasite development and the intracellular labile iron pool.
Walcourt A, Kurantsin-Mills J, Kwagyan J, Adenuga BB, Kalinowski DS, Lovejoy DB, Lane DJ, Richardson DR. Walcourt A, et al. Among authors: lovejoy db. J Inorg Biochem. 2013 Dec;129:43-51. doi: 10.1016/j.jinorgbio.2013.08.007. Epub 2013 Aug 26. J Inorg Biochem. 2013. PMID: 24028863 Free PMC article.
Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.
Kalinowski DS, Yu Y, Sharpe PC, Islam M, Liao YT, Lovejoy DB, Kumar N, Bernhardt PV, Richardson DR. Kalinowski DS, et al. Among authors: lovejoy db. J Med Chem. 2007 Jul 26;50(15):3716-29. doi: 10.1021/jm070445z. Epub 2007 Jun 30. J Med Chem. 2007. PMID: 17602603
62 results