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Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA.
Saha C, Mohanraju P, Stubbs A, Dugar G, Hoogstrate Y, Kremers GJ, van Cappellen WA, Horst-Kreft D, Laffeber C, Lebbink JHG, Bruens S, Gaskin D, Beerens D, Klunder M, Joosten R, Demmers JAA, van Gent D, Mouton JW, van der Spek PJ, van der Oost J, van Baarlen P, Louwen R. Saha C, et al. Among authors: louwen r. Sci Adv. 2020 Jun 17;6(25):eaaz4849. doi: 10.1126/sciadv.aaz4849. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32596446 Free PMC article.
Campylobacter jejuni translocation across intestinal epithelial cells is facilitated by ganglioside-like lipooligosaccharide structures.
Louwen R, Nieuwenhuis EE, van Marrewijk L, Horst-Kreft D, de Ruiter L, Heikema AP, van Wamel WJ, Wagenaar JA, Endtz HP, Samsom J, van Baarlen P, Akhmanova A, van Belkum A. Louwen R, et al. Infect Immun. 2012 Sep;80(9):3307-18. doi: 10.1128/IAI.06270-11. Epub 2012 Jul 9. Infect Immun. 2012. PMID: 22778098 Free PMC article.
A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain-Barré syndrome.
Louwen R, Horst-Kreft D, de Boer AG, van der Graaf L, de Knegt G, Hamersma M, Heikema AP, Timms AR, Jacobs BC, Wagenaar JA, Endtz HP, van der Oost J, Wells JM, Nieuwenhuis EE, van Vliet AH, Willemsen PT, van Baarlen P, van Belkum A. Louwen R, et al. Eur J Clin Microbiol Infect Dis. 2013 Feb;32(2):207-26. doi: 10.1007/s10096-012-1733-4. Epub 2012 Sep 4. Eur J Clin Microbiol Infect Dis. 2013. PMID: 22945471
22 results