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Discovery of a small-molecule protein kinase Cδ-selective activator with promising application in colon cancer therapy.
Bessa C, Soares J, Raimundo L, Loureiro JB, Gomes C, Reis F, Soares ML, Santos D, Dureja C, Chaudhuri SR, Lopez-Haber C, Kazanietz MG, Gonçalves J, Simões MF, Rijo P, Saraiva L. Bessa C, et al. Among authors: loureiro jb. Cell Death Dis. 2018 Jan 18;9(2):23. doi: 10.1038/s41419-017-0154-9. Cell Death Dis. 2018. PMID: 29348560 Free PMC article.
SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma.
Gomes S, Bosco B, Loureiro JB, Ramos H, Raimundo L, Soares J, Nazareth N, Barcherini V, Domingues L, Oliveira C, Bisio A, Piazza S, Bauer MR, Brás JP, Almeida MI, Gomes C, Reis F, Fersht AR, Inga A, Santos MMM, Saraiva L. Gomes S, et al. Among authors: loureiro jb. Cancers (Basel). 2019 Aug 10;11(8):1151. doi: 10.3390/cancers11081151. Cancers (Basel). 2019. PMID: 31405179 Free PMC article.
SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations.
Gomes AS, Ramos H, Gomes S, Loureiro JB, Soares J, Barcherini V, Monti P, Fronza G, Oliveira C, Domingues L, Bastos M, Dourado DFAR, Carvalho AL, Romão MJ, Pinheiro B, Marcelo F, Carvalho A, Santos MMM, Saraiva L. Gomes AS, et al. Among authors: loureiro jb. Biochim Biophys Acta Gen Subj. 2020 Jan;1864(1):129440. doi: 10.1016/j.bbagen.2019.129440. Epub 2019 Sep 16. Biochim Biophys Acta Gen Subj. 2020. PMID: 31536751
BRCA1/P53: Two strengths in cancer chemoprevention.
Raimundo L, Ramos H, Loureiro JB, Calheiros J, Saraiva L. Raimundo L, et al. Among authors: loureiro jb. Biochim Biophys Acta Rev Cancer. 2020 Jan;1873(1):188339. doi: 10.1016/j.bbcan.2020.188339. Epub 2020 Jan 7. Biochim Biophys Acta Rev Cancer. 2020. PMID: 31917206 Review.
21 results