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Longitudinal immune monitoring of patients with resectable esophageal adenocarcinoma treated with Neoadjuvant PD-L1 checkpoint inhibition.
van den Ende T, Ezdoglian A, Baas LM, Bakker J, Lougheed SM, Harrasser M, Waasdorp C, van Berge Henegouwen MI, Hulshof MCCM, Haj Mohammad N, van Hillegersberg R, Mook S, van der Laken CJ, van Grieken NCT, Derks S, Bijlsma MF, van Laarhoven HWM, de Gruijl TD. van den Ende T, et al. Among authors: lougheed sm. Oncoimmunology. 2023 Jul 17;12(1):2233403. doi: 10.1080/2162402X.2023.2233403. eCollection 2023. Oncoimmunology. 2023. PMID: 37470057 Free PMC article.
Functional characterization of a STAT3-dependent dendritic cell-derived CD14+ cell population arising upon IL-10-driven maturation.
Lindenberg JJ, van de Ven R, Lougheed SM, Zomer A, Santegoets SJ, Griffioen AW, Hooijberg E, van den Eertwegh AJ, Thijssen VL, Scheper RJ, Oosterhoff D, de Gruijl TD. Lindenberg JJ, et al. Among authors: lougheed sm. Oncoimmunology. 2013 Apr 1;2(4):e23837. doi: 10.4161/onci.23837. Oncoimmunology. 2013. PMID: 23734330 Free PMC article.
Constitutively active GSK3β as a means to bolster dendritic cell functionality in the face of tumour-mediated immune suppression.
López González M, Oosterhoff D, Lindenberg JJ, Milenova I, Lougheed SM, Martiáñez T, Dekker H, Quixabeira DCA, Hangalapura B, Joore J, Piersma SR, Cervera-Carrascon V, Santos JM, Scheper RJ, Verheul HMW, Jiménez CR, Van De Ven R, Hemminki A, Van Beusechem VW, De Gruijl TD. López González M, et al. Among authors: lougheed sm. Oncoimmunology. 2019 Jul 19;8(10):e1631119. doi: 10.1080/2162402X.2019.1631119. eCollection 2019. Oncoimmunology. 2019. PMID: 31646076 Free PMC article.
Local delivery of low-dose anti-CTLA-4 to the melanoma lymphatic basin leads to systemic Treg reduction and effector T cell activation.
van Pul KM, Notohardjo JCL, Fransen MF, Koster BD, Stam AGM, Chondronasiou D, Lougheed SM, Bakker J, Kandiah V, van den Tol MP, Jooss K, Vuylsteke RJCLM, van den Eertwegh AJM, de Gruijl TD. van Pul KM, et al. Among authors: lougheed sm. Sci Immunol. 2022 Jul 15;7(73):eabn8097. doi: 10.1126/sciimmunol.abn8097. Epub 2022 Jul 15. Sci Immunol. 2022. PMID: 35857579 Clinical Trial.
Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8+ T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma.
Rotman J, Heeren AM, Gassama AA, Lougheed SM, Pocorni N, Stam AGM, Bleeker MCG, Zijlmans HJMAA, Mom CH, Kenter GG, Jordanova ES, de Gruijl TD. Rotman J, et al. Among authors: lougheed sm. Clin Cancer Res. 2020 Jul 15;26(14):3791-3802. doi: 10.1158/1078-0432.CCR-19-3826. Epub 2020 Mar 27. Clin Cancer Res. 2020. PMID: 32220890
The effect of everolimus and low-dose cyclophosphamide on immune cell subsets in patients with metastatic renal cell carcinoma: results from a phase I clinical trial.
Huijts CM, Lougheed SM, Bodalal Z, van Herpen CM, Hamberg P, Tascilar M, Haanen JB, Verheul HM, de Gruijl TD, van der Vliet HJ; Dutch WIN-O Consortium. Huijts CM, et al. Among authors: lougheed sm. Cancer Immunol Immunother. 2019 Mar;68(3):503-515. doi: 10.1007/s00262-018-2288-8. Epub 2019 Jan 17. Cancer Immunol Immunother. 2019. PMID: 30652208 Free PMC article. Clinical Trial.
IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation.
Lindenberg JJ, Oosterhoff D, Sombroek CC, Lougheed SM, Hooijberg E, Stam AG, Santegoets SJ, Tijssen HJ, Buter J, Pinedo HM, van den Eertwegh AJ, Scheper RJ, Koenen HJ, van de Ven R, de Gruijl TD. Lindenberg JJ, et al. Among authors: lougheed sm. PLoS One. 2013 Jul 18;8(7):e70237. doi: 10.1371/journal.pone.0070237. Print 2013. PLoS One. 2013. PMID: 23875023 Free PMC article.
35 results