Loudon PT - Search Results

1

Single and combination herpes simplex virus type 2 glycoprotein vaccines adjuvanted with CpG oligodeoxynucleotides or monophosphoryl lipid A exhibit differential immunity that is not correlated to protection in animal models.

Khodai T, Chappell D, Christy C, Cockle P, Eyles J, Hammond D, Gore K, McCluskie MJ, Evans DM, Lang S, Loudon PT, Townend T, Wright P, West K, Bright H. Khodai T, et al. Among authors: loudon pt. Clin Vaccine Immunol. 2011 Oct;18(10):1702-9. doi: 10.1128/CVI.05071-11. Epub 2011 Aug 18. Clin Vaccine Immunol. 2011. PMID: 21852545 Free PMC article.

2

The efficacy of HSV-2 vaccines based on gD and gB is enhanced by the addition of ICP27.

Bright H, Perez DL, Christy C, Cockle P, Eyles JE, Hammond D, Khodai T, Lang S, West K, Loudon PT. Bright H, et al. Among authors: loudon pt. Vaccine. 2012 Dec 14;30(52):7529-35. doi: 10.1016/j.vaccine.2012.10.046. Epub 2012 Oct 25. Vaccine. 2012. PMID: 23103198

3

Nonreplicating vaccines can protect african green monkeys from the memphis 37 strain of respiratory syncytial virus.

Eyles JE, Johnson JE, Megati S, Roopchand V, Cockle PJ, Weeratna R, Makinen S, Brown TP, Lang S, Witko SE, Kotash CS, Li J, West K, Maldonado O, Falconer DJ, Lees C, Smith GJ, White P, Wright P, Loudon PT, Merson JR, Jansen KU, Sidhu MK. Eyles JE, et al. Among authors: loudon pt. J Infect Dis. 2013 Jul 15;208(2):319-29. doi: 10.1093/infdis/jit169. Epub 2013 Apr 17. J Infect Dis. 2013. PMID: 23596321

4

Demonstration of an anti-hyperalgesic effect of a novel pan-Trk inhibitor PF-06273340 in a battery of human evoked pain models.

Loudon P, Siebenga P, Gorman D, Gore K, Dua P, van Amerongen G, Hay JL, Groeneveld GJ, Butt RP. Loudon P, et al. Br J Clin Pharmacol. 2018 Feb;84(2):301-309. doi: 10.1111/bcp.13448. Epub 2017 Nov 28. Br J Clin Pharmacol. 2018. PMID: 29178434 Free PMC article. Clinical Trial.

5

Vaccination with cancer- and HIV infection-associated endogenous retrotransposable elements is safe and immunogenic.

Sacha JB, Kim IJ, Chen L, Ullah JH, Goodwin DA, Simmons HA, Schenkman DI, von Pelchrzim F, Gifford RJ, Nimityongskul FA, Newman LP, Wildeboer S, Lappin PB, Hammond D, Castrovinci P, Piaskowski SM, Reed JS, Beheler KA, Tharmanathan T, Zhang N, Muscat-King S, Rieger M, Fernandes C, Rumpel K, Gardner JP 2nd, Gebhard DH, Janies J, Shoieb A, Pierce BG, Trajkovic D, Rakasz E, Rong S, McCluskie M, Christy C, Merson JR, Jones RB, Nixon DF, Ostrowski MA, Loudon PT, Pruimboom-Brees IM, Sheppard NC. Sacha JB, et al. Among authors: loudon pt. J Immunol. 2012 Aug 1;189(3):1467-79. doi: 10.4049/jimmunol.1200079. Epub 2012 Jun 27. J Immunol. 2012. PMID: 22745376 Free PMC article.

6

DNA vaccination protects against an influenza challenge in a double-blind randomised placebo-controlled phase 1b clinical trial.

Jones S, Evans K, McElwaine-Johnn H, Sharpe M, Oxford J, Lambkin-Williams R, Mant T, Nolan A, Zambon M, Ellis J, Beadle J, Loudon PT. Jones S, et al. Among authors: loudon pt. Vaccine. 2009 Apr 21;27(18):2506-12. doi: 10.1016/j.vaccine.2009.02.061. Epub 2009 Feb 24. Vaccine. 2009. PMID: 19368793 Clinical Trial.

7

A Phase 1 clinical trial of Hantaan virus and Puumala virus M-segment DNA vaccines for hemorrhagic fever with renal syndrome.

Boudreau EF, Josleyn M, Ullman D, Fisher D, Dalrymple L, Sellers-Myers K, Loudon P, Rusnak J, Rivard R, Schmaljohn C, Hooper JW. Boudreau EF, et al. Vaccine. 2012 Mar 2;30(11):1951-8. doi: 10.1016/j.vaccine.2012.01.024. Epub 2012 Jan 14. Vaccine. 2012. PMID: 22248821 Clinical Trial.

8

Protection of mice from H5N1 influenza challenge by prophylactic DNA vaccination using particle mediated epidermal delivery.

Sharpe M, Lynch D, Topham S, Major D, Wood J, Loudon P. Sharpe M, et al. Vaccine. 2007 Aug 21;25(34):6392-8. doi: 10.1016/j.vaccine.2007.06.009. Epub 2007 Jun 28. Vaccine. 2007. PMID: 17640779

9

GM-CSF increases mucosal and systemic immunogenicity of an H1N1 influenza DNA vaccine administered into the epidermis of non-human primates.

Loudon PT, Yager EJ, Lynch DT, Narendran A, Stagnar C, Franchini AM, Fuller JT, White PA, Nyuandi J, Wiley CA, Murphey-Corb M, Fuller DH. Loudon PT, et al. PLoS One. 2010 Jun 8;5(6):e11021. doi: 10.1371/journal.pone.0011021. PLoS One. 2010. PMID: 20544035 Free PMC article.

10

Acute kidney injury observed during phase 1 clinical trials of a novel xanthine oxidase/URAT1 dual inhibitor PF-06743649.

Dua P, Gurrell R, Kirby S, Sudworth M, Loudon PT. Dua P, et al. Among authors: loudon pt. Clin Rheumatol. 2016 Aug;35(8):2045-2051. doi: 10.1007/s10067-016-3273-2. Epub 2016 Apr 19. Clin Rheumatol. 2016. PMID: 27094945 Clinical Trial.

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