Lou HJ - Search Results

1

A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding.

Terekhov SS, Mokrushina YA, Nazarov AS, Zlobin A, Zalevsky A, Bourenkov G, Golovin A, Belogurov A Jr, Osterman IA, Kulikova AA, Mitkevich VA, Lou HJ, Turk BE, Wilmanns M, Smirnov IV, Altman S, Gabibov AG. Terekhov SS, et al. Among authors: lou hj. Sci Adv. 2020 Jun 24;6(26):eaaz9861. doi: 10.1126/sciadv.aaz9861. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32637600 Free PMC article.

2

Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase.

Shehata SN, Hunter RW, Ohta E, Peggie MW, Lou HJ, Sicheri F, Zeqiraj E, Turk BE, Sakamoto K. Shehata SN, et al. Among authors: lou hj. Cell Signal. 2012 Nov;24(11):2085-94. doi: 10.1016/j.cellsig.2012.06.018. Epub 2012 Jul 11. Cell Signal. 2012. PMID: 22796189 Free PMC article.

3

Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate.

Ha BH, Davis MJ, Chen C, Lou HJ, Gao J, Zhang R, Krauthammer M, Halaban R, Schlessinger J, Turk BE, Boggon TJ. Ha BH, et al. Among authors: lou hj. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16107-12. doi: 10.1073/pnas.1214447109. Epub 2012 Sep 17. Proc Natl Acad Sci U S A. 2012. PMID: 22988085 Free PMC article.

4

Substrate and inhibitor specificity of the type II p21-activated kinase, PAK6.

Gao J, Ha BH, Lou HJ, Morse EM, Zhang R, Calderwood DA, Turk BE, Boggon TJ. Gao J, et al. Among authors: lou hj. PLoS One. 2013 Oct 28;8(10):e77818. doi: 10.1371/journal.pone.0077818. eCollection 2013. PLoS One. 2013. PMID: 24204982 Free PMC article.

5

Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.

Chen C, Ha BH, Thévenin AF, Lou HJ, Zhang R, Yip KY, Peterson JR, Gerstein M, Kim PM, Filippakopoulos P, Knapp S, Boggon TJ, Turk BE. Chen C, et al. Among authors: lou hj. Mol Cell. 2014 Jan 9;53(1):140-7. doi: 10.1016/j.molcel.2013.11.013. Epub 2013 Dec 26. Mol Cell. 2014. PMID: 24374310 Free PMC article.

6

The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice.

Etheridge RD, Alaganan A, Tang K, Lou HJ, Turk BE, Sibley LD. Etheridge RD, et al. Among authors: lou hj. Cell Host Microbe. 2014 May 14;15(5):537-50. doi: 10.1016/j.chom.2014.04.002. Cell Host Microbe. 2014. PMID: 24832449 Free PMC article.

7

An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.

Goodwin JM, Svensson RU, Lou HJ, Winslow MM, Turk BE, Shaw RJ. Goodwin JM, et al. Among authors: lou hj. Mol Cell. 2014 Aug 7;55(3):436-50. doi: 10.1016/j.molcel.2014.06.021. Epub 2014 Jul 17. Mol Cell. 2014. PMID: 25042806 Free PMC article.

8

Ancestral resurrection reveals evolutionary mechanisms of kinase plasticity.

Howard CJ, Hanson-Smith V, Kennedy KJ, Miller CJ, Lou HJ, Johnson AD, Turk BE, Holt LJ. Howard CJ, et al. Among authors: lou hj. Elife. 2014 Oct 13;3:e04126. doi: 10.7554/eLife.04126. Elife. 2014. PMID: 25310241 Free PMC article.

9

Biochemical characterization of FIKK8--A unique protein kinase from the malaria parasite Plasmodium falciparum and other apicomplexans.

Osman KT, Lou HJ, Qiu W, Brand V, Edwards AM, Turk BE, Hui R. Osman KT, et al. Among authors: lou hj. Mol Biochem Parasitol. 2015 Jun;201(2):85-9. doi: 10.1016/j.molbiopara.2015.06.002. Epub 2015 Jun 22. Mol Biochem Parasitol. 2015. PMID: 26112892 Free PMC article.

10

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.

Egan DF, Chun MG, Vamos M, Zou H, Rong J, Miller CJ, Lou HJ, Raveendra-Panickar D, Yang CC, Sheffler DJ, Teriete P, Asara JM, Turk BE, Cosford ND, Shaw RJ. Egan DF, et al. Among authors: lou hj. Mol Cell. 2015 Jul 16;59(2):285-97. doi: 10.1016/j.molcel.2015.05.031. Epub 2015 Jun 25. Mol Cell. 2015. PMID: 26118643 Free PMC article.

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