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Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Leng H, Zhang H, Li L, Zhang S, Wang Y, Chavda SJ, Galas-Filipowicz D, Lou H, Ersek A, Morris EV, Sezgin E, Lee YH, Li Y, Lechuga-Vieco AV, Tian M, Mi JQ, Yong K, Zhong Q, Edwards CM, Simon AK, Horwood NJ. Leng H, et al. Among authors: lou h. Nat Commun. 2022 Dec 22;13(1):7868. doi: 10.1038/s41467-022-35358-3. Nat Commun. 2022. PMID: 36550101 Free PMC article.
Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia.
Liang Z, Damianou A, Vendrell I, Jenkins E, Lassen FH, Washer SJ, Grigoriou A, Liu G, Yi G, Lou H, Cao F, Zheng X, Fernandes RA, Dong T, Tate EW, Di Daniel E, Kessler BM. Liang Z, et al. Among authors: lou h. Cell Rep. 2024 Apr 25;43(5):114152. doi: 10.1016/j.celrep.2024.114152. Online ahead of print. Cell Rep. 2024. PMID: 38669140 Free article.
Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma.
Carroll TM, Chadwick JA, Owen RP, White MJ, Kaplinsky J, Peneva I, Frangou A, Xie PF, Chang J, Roth A, Amess B, James SA, Rei M, Fuchs HS, McCann KJ, Omiyale AO, Jacobs BA, Lord SR, Norris-Bulpitt S, Dobbie ST, Griffiths L, Ramirez KA, Ricciardi T, Macri MJ, Ryan A, Venhaus RR, Van den Eynde BJ, Karydis I, Schuster-Böckler B, Middleton MR, Lu X; LUD2015-005 Project Team. Carroll TM, et al. Cancer Cell. 2023 Jul 10;41(7):1222-1241.e7. doi: 10.1016/j.ccell.2023.06.006. Cancer Cell. 2023. PMID: 37433281 Free article.
Extracellular DNA and autoimmune diseases.
Lou H, Pickering MC. Lou H, et al. Cell Mol Immunol. 2018 Aug;15(8):746-755. doi: 10.1038/cmi.2017.136. Epub 2018 Mar 19. Cell Mol Immunol. 2018. PMID: 29553134 Free PMC article. Review.
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.
Ma J, Al Moussawi K, Lou H, Chan HF, Wang Y, Chadwick J, Phetsouphanh C, Slee EA, Zhong S, Leissing TM, Roth A, Qin X, Chen S, Yin J, Ratnayaka I, Hu Y, Louphrasitthiphol P, Taylor L, Bettencourt PJG, Muers M, Greaves DR, McShane H, Goldin R, Soilleux EJ, Coleman ML, Ratcliffe PJ, Lu X. Ma J, et al. Among authors: lou h. Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2309957121. doi: 10.1073/pnas.2309957121. Epub 2024 Feb 29. Proc Natl Acad Sci U S A. 2024. PMID: 38422022 Free PMC article.
2,016 results