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SALL4 is a CRL3REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma.
Lospinoso Severini L, Loricchio E, Navacci S, Basili I, Alfonsi R, Bernardi F, Moretti M, Conenna M, Cucinotta A, Coni S, Petroni M, De Smaele E, Giannini G, Maroder M, Canettieri G, Mastronuzzi A, Guardavaccaro D, Ayrault O, Infante P, Bufalieri F, Di Marcotullio L. Lospinoso Severini L, et al. Cell Death Differ. 2024 Feb;31(2):170-187. doi: 10.1038/s41418-023-01246-6. Epub 2023 Dec 7. Cell Death Differ. 2024. PMID: 38062245 Free PMC article.
The RIG-I agonist M8 triggers cell death and natural killer cell activation in human papillomavirus-associated cancer and potentiates cisplatin cytotoxicity.
Girone C, Calati F, Lo Cigno I, Salvi V, Tassinari V, Schioppa T, Borgogna C, Lospinoso Severini L, Hiscott J, Cerboni C, Soriani A, Bosisio D, Gariglio M. Girone C, et al. Among authors: lospinoso severini l. Cancer Immunol Immunother. 2023 Sep;72(9):3097-3110. doi: 10.1007/s00262-023-03483-7. Epub 2023 Jun 25. Cancer Immunol Immunother. 2023. PMID: 37356050 Free PMC article.
SMA-miRs (miR-181a-5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples.
Abiusi E, Infante P, Cagnoli C, Lospinoso Severini L, Pane M, Coratti G, Pera MC, D'Amico A, Diano F, Novelli A, Spartano S, Fiori S, Baranello G, Moroni I, Mora M, Pasanisi MB, Pocino K, Le Pera L, D'Amico D, Travaglini L, Ria F, Bruno C, Locatelli D, Bertini ES, Morandi LO, Mercuri E, Di Marcotullio L, Tiziano FD. Abiusi E, et al. Among authors: lospinoso severini l. Elife. 2021 Sep 20;10:e68054. doi: 10.7554/eLife.68054. Elife. 2021. PMID: 34542403 Free PMC article.
Specific Protein 1 and p53 Interplay Modulates the Expression of the KCTD-Containing Cullin3 Adaptor Suppressor of Hedgehog 2.
Angrisani A, Di Fiore A, Di Trani CA, Fonte S, Petroni M, Lospinoso Severini L, Bordin F, Belloni L, Ferretti E, Canettieri G, Moretti M, De Smaele E. Angrisani A, et al. Among authors: lospinoso severini l. Front Cell Dev Biol. 2021 Apr 8;9:638508. doi: 10.3389/fcell.2021.638508. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33898425 Free PMC article.
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma.
Infante P, Malfanti A, Quaglio D, Balducci S, De Martin S, Bufalieri F, Mastrotto F, Basili I, Garofalo M, Lospinoso Severini L, Mori M, Manni I, Moretti M, Nicoletti C, Piaggio G, Caliceti P, Botta B, Ghirga F, Salmaso S, Di Marcotullio L. Infante P, et al. Among authors: lospinoso severini l. Cancer Lett. 2021 Feb 28;499:220-231. doi: 10.1016/j.canlet.2020.11.028. Epub 2020 Nov 26. Cancer Lett. 2021. PMID: 33249196 Free article.
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma.
Lospinoso Severini L, Ghirga F, Bufalieri F, Quaglio D, Infante P, Di Marcotullio L. Lospinoso Severini L, et al. Expert Opin Ther Targets. 2020 Nov;24(11):1159-1181. doi: 10.1080/14728222.2020.1823967. Epub 2020 Sep 29. Expert Opin Ther Targets. 2020. PMID: 32990091 Review.
The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I.
Bufalieri F, Caimano M, Lospinoso Severini L, Basili I, Paglia F, Sampirisi L, Loricchio E, Petroni M, Canettieri G, Santoro A, D'Angelo L, Infante P, Di Marcotullio L. Bufalieri F, et al. Among authors: lospinoso severini l. Cancers (Basel). 2020 Jan 30;12(2):321. doi: 10.3390/cancers12020321. Cancers (Basel). 2020. PMID: 32019099 Free PMC article.
15 results