Losiewicz MD - Search Results

1

Long-term exposure to low concentrations of MC-LR induces blood-testis barrier damage through the RhoA/ROCK pathway.

Liu H, Zeng X, Ma Y, Chen X, Losiewicz MD, Du X, Tian Z, Zhang S, Shi L, Zhang H, Yang F. Liu H, et al. Among authors: losiewicz md. Ecotoxicol Environ Saf. 2022 May 1;236:113454. doi: 10.1016/j.ecoenv.2022.113454. Epub 2022 Mar 31. Ecotoxicol Environ Saf. 2022. PMID: 35367887 Free article.

2

Role of microRNA-122 in microcystin-leucine arginine-induced dysregulation of hepatic iron homeostasis in mice.

Wang R, Liu X, Wu J, Liu H, Wang W, Chen X, Yuan L, Wang Y, Du X, Ma Y, Losiewicz MD, Zhang X, Zhang H. Wang R, et al. Among authors: losiewicz md. Environ Toxicol. 2020 Aug;35(8):822-830. doi: 10.1002/tox.22918. Epub 2020 Mar 14. Environ Toxicol. 2020. PMID: 32170997

3

The activated ATM/p53 pathway promotes autophagy in response to oxidative stress-mediated DNA damage induced by Microcystin-LR in male germ cells.

Tian Z, Liu H, Chen X, Losiewicz MD, Wang R, Du X, Wang B, Ma Y, Zhang S, Shi L, Guo X, Wang Y, Zhang B, Yuan S, Zeng X, Zhang H. Tian Z, et al. Among authors: losiewicz md. Ecotoxicol Environ Saf. 2021 Dec 20;227:112919. doi: 10.1016/j.ecoenv.2021.112919. Epub 2021 Oct 26. Ecotoxicol Environ Saf. 2021. PMID: 34715501 Free article.

4

Chronic Exposure to Environmentally Relevant Concentrations of Microcystin-Leucine Arginine Causes Lung Barrier Damage through PP2A Activity Inhibition and Claudin1 Ubiquitination.

Liu H, Zeng X, Wang Y, Losiewicz MD, Chen X, Du X, Wang Y, Zhang B, Guo X, Yuan S, Yang F, Zhang H. Liu H, et al. Among authors: losiewicz md. J Agric Food Chem. 2022 Sep 7;70(35):10907-10918. doi: 10.1021/acs.jafc.2c05207. Epub 2022 Aug 26. J Agric Food Chem. 2022. PMID: 36026589

5

p53-Dependent pathway and the opening of mPTP mediate the apoptosis of co-cultured Sertoli-germ cells induced by microcystin-LR.

Wu J, Liu H, Huang H, Yuan L, Liu C, Wang Y, Cheng X, Zhuang D, Xu M, Chen X, Losiewicz MD, Zhang H. Wu J, et al. Among authors: losiewicz md. Environ Toxicol. 2019 Oct;34(10):1074-1084. doi: 10.1002/tox.22808. Epub 2019 Jun 3. Environ Toxicol. 2019. PMID: 31157505

6

The Diversity of Cyanobacterial Toxins on Structural Characterization, Distribution and Identification: A Systematic Review.

Du X, Liu H, Yuan L, Wang Y, Ma Y, Wang R, Chen X, Losiewicz MD, Guo H, Zhang H. Du X, et al. Among authors: losiewicz md. Toxins (Basel). 2019 Sep 12;11(9):530. doi: 10.3390/toxins11090530. Toxins (Basel). 2019. PMID: 31547379 Free PMC article.

7

A combined gene expression and functional study reveals the crosstalk between N-Myc and differentiation-inducing microRNAs in neuroblastoma cells.

Zhao Z, Ma X, Shelton SD, Sung DC, Li M, Hernandez D, Zhang M, Losiewicz MD, Chen Y, Pertsemlidis A, Yu X, Liu Y, Du L. Zhao Z, et al. Among authors: losiewicz md. Oncotarget. 2016 Nov 29;7(48):79372-79387. doi: 10.18632/oncotarget.12676. Oncotarget. 2016. PMID: 27764804 Free PMC article.

8

Early induction of apoptosis in hematopoietic cell lines after exposure to flavopiridol.

Parker BW, Kaur G, Nieves-Neira W, Taimi M, Kohlhagen G, Shimizu T, Losiewicz MD, Pommier Y, Sausville EA, Senderowicz AM. Parker BW, et al. Among authors: losiewicz md. Blood. 1998 Jan 15;91(2):458-65. Blood. 1998. PMID: 9427698 Free article.

9

Flavopiridol (L86 8275; NSC 649890), a new kinase inhibitor for tumor therapy.

Sedlacek H, Czech J, Naik R, Kaur G, Worland P, Losiewicz M, Parker B, Carlson B, Smith A, Senderowicz A, Sausville E. Sedlacek H, et al. Int J Oncol. 1996 Dec;9(6):1143-68. doi: 10.3892/ijo.9.6.1143. Int J Oncol. 1996. PMID: 21541623

10

Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.

Losiewicz MD, Carlson BA, Kaur G, Sausville EA, Worland PJ. Losiewicz MD, et al. Biochem Biophys Res Commun. 1994 Jun 15;201(2):589-95. doi: 10.1006/bbrc.1994.1742. Biochem Biophys Res Commun. 1994. PMID: 8002990

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