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cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission.
Ramdani G, Naissant B, Thompson E, Breil F, Lorthiois A, Dupuy F, Cummings R, Duffier Y, Corbett Y, Mercereau-Puijalon O, Vernick K, Taramelli D, Baker DA, Langsley G, Lavazec C. Ramdani G, et al. Among authors: lorthiois a. PLoS Pathog. 2015 May 7;11(5):e1004815. doi: 10.1371/journal.ppat.1004815. eCollection 2015 May. PLoS Pathog. 2015. PMID: 25951195 Free PMC article.
Plasmodium Merozoite TRAP Family Protein Is Essential for Vacuole Membrane Disruption and Gamete Egress from Erythrocytes.
Bargieri DY, Thiberge S, Tay CL, Carey AF, Rantz A, Hischen F, Lorthiois A, Straschil U, Singh P, Singh S, Triglia T, Tsuboi T, Cowman A, Chitnis C, Alano P, Baum J, Pradel G, Lavazec C, Ménard R. Bargieri DY, et al. Among authors: lorthiois a. Cell Host Microbe. 2016 Nov 9;20(5):618-630. doi: 10.1016/j.chom.2016.10.015. Cell Host Microbe. 2016. PMID: 27832590 Free PMC article.
Role of a patatin-like phospholipase in Plasmodium falciparum gametogenesis and malaria transmission.
Singh P, Alaganan A, More KR, Lorthiois A, Thiberge S, Gorgette O, Guillotte Blisnick M, Guglielmini J, Aguilera SS, Touqui L, Singh S, Chitnis CE. Singh P, et al. Among authors: lorthiois a. Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17498-17508. doi: 10.1073/pnas.1900266116. Epub 2019 Aug 14. Proc Natl Acad Sci U S A. 2019. PMID: 31413195 Free PMC article.
Plasmodium falciparum sexual parasites develop in human erythroblasts and affect erythropoiesis.
Neveu G, Richard C, Dupuy F, Behera P, Volpe F, Subramani PA, Marcel-Zerrougui B, Vallin P, Andrieu M, Minz AM, Azar N, Martins RM, Lorthiois A, Gazeau F, Lopez-Rubio JJ, Mazier D, Silva AKA, Satpathi S, Wassmer SC, Verdier F, Lavazec C. Neveu G, et al. Among authors: lorthiois a. Blood. 2020 Sep 17;136(12):1381-1393. doi: 10.1182/blood.2019004746. Blood. 2020. PMID: 32589714 Free PMC article.
Infectivity of Plasmodium falciparum sporozoites determines emerging parasitemia in infected volunteers.
McCall MBB, Wammes LJ, Langenberg MCC, van Gemert GJ, Walk J, Hermsen CC, Graumans W, Koelewijn R, Franetich JF, Chishimba S, Gerdsen M, Lorthiois A, van de Vegte M, Mazier D, Bijker EM, van Hellemond JJ, van Genderen PJJ, Sauerwein RW. McCall MBB, et al. Among authors: lorthiois a. Sci Transl Med. 2017 Jun 21;9(395):eaag2490. doi: 10.1126/scitranslmed.aag2490. Sci Transl Med. 2017. PMID: 28637923
Plasmodium falciparum full life cycle and Plasmodium ovale liver stages in humanized mice.
Soulard V, Bosson-Vanga H, Lorthiois A, Roucher C, Franetich JF, Zanghi G, Bordessoulles M, Tefit M, Thellier M, Morosan S, Le Naour G, Capron F, Suemizu H, Snounou G, Moreno-Sabater A, Mazier D. Soulard V, et al. Among authors: lorthiois a. Nat Commun. 2015 Jul 24;6:7690. doi: 10.1038/ncomms8690. Nat Commun. 2015. PMID: 26205537 Free PMC article.
Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum.
Nardella F, Dobrescu I, Hassan H, Rodrigues F, Thiberge S, Mancio-Silva L, Tafit A, Jallet C, Cadet-Daniel V, Goussin S, Lorthiois A, Menon Y, Molinier N, Pechalrieu D, Long C, Sautel F, Matondo M, Duchateau M, Médard G, Witkowski B, Scherf A, Halby L, Arimondo PB. Nardella F, et al. Among authors: lorthiois a. iScience. 2023 Jan 11;26(2):105940. doi: 10.1016/j.isci.2023.105940. eCollection 2023 Feb 17. iScience. 2023. PMID: 36718363 Free PMC article.
18 results