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Stable isotope-resolved metabolomics and applications for drug development.
Fan TW, Lorkiewicz PK, Sellers K, Moseley HN, Higashi RM, Lane AN. Fan TW, et al. Among authors: lorkiewicz pk. Pharmacol Ther. 2012 Mar;133(3):366-91. doi: 10.1016/j.pharmthera.2011.12.007. Epub 2011 Dec 23. Pharmacol Ther. 2012. PMID: 22212615 Free PMC article. Review.
Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease.
Guin S, Pollard C, Ru Y, Ritterson Lew C, Duex JE, Dancik G, Owens C, Spencer A, Knight S, Holemon H, Gupta S, Hansel D, Hellerstein M, Lorkiewicz P, Lane AN, Fan TW, Theodorescu D. Guin S, et al. J Natl Cancer Inst. 2014 Apr 3;106(5):dju062. doi: 10.1093/jnci/dju062. J Natl Cancer Inst. 2014. PMID: 24700805 Free PMC article.
Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.
Xie H, Hanai J, Ren JG, Kats L, Burgess K, Bhargava P, Signoretti S, Billiard J, Duffy KJ, Grant A, Wang X, Lorkiewicz PK, Schatzman S, Bousamra M 2nd, Lane AN, Higashi RM, Fan TW, Pandolfi PP, Sukhatme VP, Seth P. Xie H, et al. Among authors: lorkiewicz pk. Cell Metab. 2014 May 6;19(5):795-809. doi: 10.1016/j.cmet.2014.03.003. Epub 2014 Apr 10. Cell Metab. 2014. PMID: 24726384 Free PMC article.
68 results