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TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure.
Sci Transl Med. 2022 Nov 2;14(669):eabm3565. doi: 10.1126/scitranslmed.abm3565. Epub 2022 Nov 2.
Sci Transl Med. 2022.
PMID: 36322626
A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer.
Boukouris AE, Zhang Y, Saleme B, Kinnaird A, Zhao YY, Liu Y, Zervopoulos SD, Das SK, Mittal RD, Haromy A, Lorenzana-Carrillo MA, Krysler AR, Cromwell CR, Hubbard BP, Sutendra G, Michelakis ED.
Boukouris AE, et al. Among authors: lorenzana carrillo ma.
Cell Rep. 2022 Mar 15;38(11):110511. doi: 10.1016/j.celrep.2022.110511.
Cell Rep. 2022.
PMID: 35294884
Free article.
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SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes.
Zhang Y, Zervopoulos SD, Boukouris AE, Lorenzana-Carrillo MA, Saleme B, Webster L, Liu Y, Haromy A, Tabatabaei Dakhili SA, Ussher JR, Sutendra G, Michelakis ED.
Zhang Y, et al. Among authors: lorenzana carrillo ma.
J Am Heart Assoc. 2021 Dec 7;10(23):e020451. doi: 10.1161/JAHA.120.020451. Epub 2021 Oct 30.
J Am Heart Assoc. 2021.
PMID: 34719264
Free PMC article.
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p53-Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio-oncology.
Saleme B, Das SK, Zhang Y, Boukouris AE, Lorenzana Carrillo MA, Jovel J, Wagg CS, Lopaschuk GD, Michelakis ED, Sutendra G.
Saleme B, et al. Among authors: lorenzana carrillo ma.
J Am Heart Assoc. 2020 Aug 4;9(15):e017247. doi: 10.1161/JAHA.120.017247. Epub 2020 Jul 29.
J Am Heart Assoc. 2020.
PMID: 32750288
Free PMC article.
No abstract available.
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Endothelial cells of different organs exhibit heterogeneity in von Willebrand factor expression in response to hypoxia.
Mojiri A, Alavi P, Lorenzana Carrillo MA, Nakhaei-Nejad M, Sergi CM, Thebaud B, Aird WC, Jahroudi N.
Mojiri A, et al. Among authors: lorenzana carrillo ma.
Atherosclerosis. 2019 Mar;282:1-10. doi: 10.1016/j.atherosclerosis.2019.01.002. Epub 2019 Jan 12.
Atherosclerosis. 2019.
PMID: 30665023
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