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Teixobactin kills bacteria by a two-pronged attack on the cell envelope.
Shukla R, Lavore F, Maity S, Derks MGN, Jones CR, Vermeulen BJA, Melcrová A, Morris MA, Becker LM, Wang X, Kumar R, Medeiros-Silva J, van Beekveld RAM, Bonvin AMJJ, Lorent JH, Lelli M, Nowick JS, MacGillavry HD, Peoples AJ, Spoering AL, Ling LL, Hughes DE, Roos WH, Breukink E, Lewis K, Weingarth M. Shukla R, et al. Among authors: lorent jh. Nature. 2022 Aug;608(7922):390-396. doi: 10.1038/s41586-022-05019-y. Epub 2022 Aug 3. Nature. 2022. PMID: 35922513 Free PMC article.
Mode of action of teixobactins in cellular membranes.
Shukla R, Medeiros-Silva J, Parmar A, Vermeulen BJA, Das S, Paioni AL, Jekhmane S, Lorent J, Bonvin AMJJ, Baldus M, Lelli M, Veldhuizen EJA, Breukink E, Singh I, Weingarth M. Shukla R, et al. Nat Commun. 2020 Jun 5;11(1):2848. doi: 10.1038/s41467-020-16600-2. Nat Commun. 2020. PMID: 32503964 Free PMC article.
Metabolic labeling of the bacterial peptidoglycan by functionalized glucosamine.
Xu Y, Hernández-Rocamora VM, Lorent JH, Cox R, Wang X, Bao X, Stel M, Vos G, van den Bos RM, Pieters RJ, Gray J, Vollmer W, Breukink E. Xu Y, et al. Among authors: lorent jh. iScience. 2022 Jul 12;25(8):104753. doi: 10.1016/j.isci.2022.104753. eCollection 2022 Aug 19. iScience. 2022. PMID: 35942089 Free PMC article.
Domain Stability in Biomimetic Membranes Driven by Lipid Polyunsaturation.
Lin X, Lorent JH, Skinkle AD, Levental KR, Waxham MN, Gorfe AA, Levental I. Lin X, et al. Among authors: lorent jh. J Phys Chem B. 2016 Nov 23;120(46):11930-11941. doi: 10.1021/acs.jpcb.6b06815. Epub 2016 Nov 10. J Phys Chem B. 2016. PMID: 27797198 Free PMC article.
Multifaceted Activities of Seven Nanobodies against Complement C4b.
De la O Becerra KI, Oosterheert W, van den Bos RM, Xenaki KT, Lorent JH, Ruyken M, Schouten A, Rooijakkers SHM, van Bergen En Henegouwen PMP, Gros P. De la O Becerra KI, et al. Among authors: lorent jh. J Immunol. 2022 May 1;208(9):2207-2219. doi: 10.4049/jimmunol.2100647. Epub 2022 Apr 15. J Immunol. 2022. PMID: 35428691 Free PMC article.
26 results