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Clonal dominance defines metastatic dissemination in pancreatic cancer.
Sci Adv. 2024 Mar 15;10(11):eadd9342. doi: 10.1126/sciadv.add9342. Epub 2024 Mar 13.
Sci Adv. 2024.
PMID: 38478609
Free article.
Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis.
Del Poggetto E, Ho IL, Balestrieri C, Yen EY, Zhang S, Citron F, Shah R, Corti D, Diaferia GR, Li CY, Loponte S, Carbone F, Hayakawa Y, Valenti G, Jiang S, Sapio L, Jiang H, Dey P, Gao S, Deem AK, Rose-John S, Yao W, Ying H, Rhim AD, Genovese G, Heffernan TP, Maitra A, Wang TC, Wang L, Draetta GF, Carugo A, Natoli G, Viale A.
Del Poggetto E, et al. Among authors: loponte s.
Science. 2021 Sep 17;373(6561):eabj0486. doi: 10.1126/science.abj0486. Epub 2021 Sep 17.
Science. 2021.
PMID: 34529467
Free PMC article.
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Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer.
Inoue A, Robinson FS, Minelli R, Tomihara H, Rizi BS, Rose JL, Kodama T, Srinivasan S, Harris AL, Zuniga AM, Mullinax RA, Ma X, Seth S, Daniele JR, Peoples MD, Loponte S, Akdemir KC, Khor TO, Feng N, Roszik J, Sobieski MM, Brunell D, Stephan C, Giuliani V, Deem AK, Shingu T, Deribe YL, Menter DG, Heffernan TP, Viale A, Bristow CA, Kopetz S, Draetta GF, Genovese G, Carugo A.
Inoue A, et al. Among authors: loponte s.
Gastroenterology. 2021 Jul;161(1):196-210. doi: 10.1053/j.gastro.2021.03.022. Epub 2021 Mar 19.
Gastroenterology. 2021.
PMID: 33745946
Free PMC article.
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The Many Facets of Tumor Heterogeneity: Is Metabolism Lagging Behind?
Loponte S, Lovisa S, Deem AK, Carugo A, Viale A.
Loponte S, et al.
Cancers (Basel). 2019 Oct 16;11(10):1574. doi: 10.3390/cancers11101574.
Cancers (Basel). 2019.
PMID: 31623133
Free PMC article.
Review.
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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Malouf GG, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Sgambato A, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G.
Carugo A, et al. Among authors: loponte s.
Cancer Cell. 2019 Feb 11;35(2):204-220.e9. doi: 10.1016/j.ccell.2019.01.006.
Cancer Cell. 2019.
PMID: 30753823
Free PMC article.
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Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors.
Seth S, Li CY, Ho IL, Corti D, Loponte S, Sapio L, Del Poggetto E, Yen EY, Robinson FS, Peoples M, Karpinets T, Deem AK, Kumar T, Song X, Jiang S, Kang Y, Fleming J, Kim M, Zhang J, Maitra A, Heffernan TP, Giuliani V, Genovese G, Futreal A, Draetta GF, Carugo A, Viale A.
Seth S, et al. Among authors: loponte s.
Cell Rep. 2019 Feb 5;26(6):1518-1532.e9. doi: 10.1016/j.celrep.2019.01.048.
Cell Rep. 2019.
PMID: 30726735
Free article.
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Dynamic phosphorylation of Histone Deacetylase 1 by Aurora kinases during mitosis regulates zebrafish embryos development.
Loponte S, Segré CV, Senese S, Miccolo C, Santaguida S, Deflorian G, Citro S, Mattoscio D, Pisati F, Moser MA, Visintin R, Seiser C, Chiocca S.
Loponte S, et al.
Sci Rep. 2016 Jul 26;6:30213. doi: 10.1038/srep30213.
Sci Rep. 2016.
PMID: 27458029
Free PMC article.
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A monoclonal antibody specific for prophase phosphorylation of histone deacetylase 1: a readout for early mitotic cells.
Segré CV, Senese S, Loponte S, Santaguida S, Soffientini P, Grigorean G, Cinquanta M, Ossolengo G, Seiser C, Chiocca S.
Segré CV, et al. Among authors: loponte s.
MAbs. 2016;8(1):37-42. doi: 10.1080/19420862.2015.1098795. Epub 2015 Oct 14.
MAbs. 2016.
PMID: 26467746
Free PMC article.
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