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Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.
Cassetta L, Fragkogianni S, Sims AH, Swierczak A, Forrester LM, Zhang H, Soong DYH, Cotechini T, Anur P, Lin EY, Fidanza A, Lopez-Yrigoyen M, Millar MR, Urman A, Ai Z, Spellman PT, Hwang ES, Dixon JM, Wiechmann L, Coussens LM, Smith HO, Pollard JW. Cassetta L, et al. Among authors: lopez yrigoyen m. Cancer Cell. 2019 Apr 15;35(4):588-602.e10. doi: 10.1016/j.ccell.2019.02.009. Epub 2019 Mar 28. Cancer Cell. 2019. PMID: 30930117 Free PMC article.
Macrophage targeting in cancer.
Lopez-Yrigoyen M, Cassetta L, Pollard JW. Lopez-Yrigoyen M, et al. Ann N Y Acad Sci. 2021 Sep;1499(1):18-41. doi: 10.1111/nyas.14377. Epub 2020 May 22. Ann N Y Acad Sci. 2021. PMID: 32445205 Review.
A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and in vivo tracking of therapeutic cells.
Lopez-Yrigoyen M, Fidanza A, Cassetta L, Axton RA, Taylor AH, Meseguer-Ripolles J, Tsakiridis A, Wilson V, Hay DC, Pollard JW, Forrester LM. Lopez-Yrigoyen M, et al. Philos Trans R Soc Lond B Biol Sci. 2018 Jul 5;373(1750):20170219. doi: 10.1098/rstb.2017.0219. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29786554 Free PMC article.
An all-in-one UniSam vector system for efficient gene activation.
Fidanza A, Lopez-Yrigoyen M, Romanò N, Jones R, Taylor AH, Forrester LM. Fidanza A, et al. Among authors: lopez yrigoyen m. Sci Rep. 2017 Jul 25;7(1):6394. doi: 10.1038/s41598-017-06468-6. Sci Rep. 2017. PMID: 28743878 Free PMC article.
SplitAx: A novel method to assess the function of engineered nucleases.
Axton RA, Haideri SS, Lopez-Yrigoyen M, Taylor HA, Forrester LM. Axton RA, et al. Among authors: lopez yrigoyen m. PLoS One. 2017 Feb 17;12(2):e0171698. doi: 10.1371/journal.pone.0171698. eCollection 2017. PLoS One. 2017. PMID: 28212417 Free PMC article.
Single-cell analyses and machine learning define hematopoietic progenitor and HSC-like cells derived from human PSCs.
Fidanza A, Stumpf PS, Ramachandran P, Tamagno S, Babtie A, Lopez-Yrigoyen M, Taylor AH, Easterbrook J, Henderson BEP, Axton R, Henderson NC, Medvinsky A, Ottersbach K, Romanò N, Forrester LM. Fidanza A, et al. Among authors: lopez yrigoyen m. Blood. 2020 Dec 17;136(25):2893-2904. doi: 10.1182/blood.2020006229. Blood. 2020. PMID: 32614947 Free PMC article.