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Targeting the neuronal calcium sensor DREAM with small-molecules for Huntington's disease treatment.
Sci Rep. 2019 May 13;9(1):7260. doi: 10.1038/s41598-019-43677-7.
Sci Rep. 2019.
PMID: 31086218
Free PMC article.
Inhibition of DREAM-ATF6 interaction delays onset of cognition deficit in a mouse model of Huntington's disease.
López-Hurtado A, Burgos DF, González P, Dopazo XM, González V, Rábano A, Mellström B, Naranjo JR.
López-Hurtado A, et al.
Mol Brain. 2018 Mar 9;11(1):13. doi: 10.1186/s13041-018-0359-6.
Mol Brain. 2018.
PMID: 29523177
Free PMC article.
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Inhibition of the Neuronal Calcium Sensor DREAM Modulates Presenilin-2 Endoproteolysis.
Naranjo R, González P, Lopez-Hurtado A, Dopazo XM, Mellström B, Naranjo JR.
Naranjo R, et al. Among authors: lopez hurtado a.
Front Mol Neurosci. 2018 Dec 3;11:449. doi: 10.3389/fnmol.2018.00449. eCollection 2018.
Front Mol Neurosci. 2018.
PMID: 30559648
Free PMC article.
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Identification of IQM-266, a Novel DREAM Ligand That Modulates KV4 Currents.
Peraza DA, Cercós P, Miaja P, Merinero YG, Lagartera L, Socuéllamos PG, Izquierdo García C, Sánchez SA, López-Hurtado A, Martín-Martínez M, Olivos-Oré LA, Naranjo JR, Artalejo AR, Gutiérrez-Rodríguez M, Valenzuela C.
Peraza DA, et al. Among authors: lopez hurtado a.
Front Mol Neurosci. 2019 Feb 4;12:11. doi: 10.3389/fnmol.2019.00011. eCollection 2019.
Front Mol Neurosci. 2019.
PMID: 30787866
Free PMC article.
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