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Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis.
FASEB J. 2016 Oct;30(10):3321-3333. doi: 10.1096/fj.201500138RR. Epub 2016 Jun 24.
FASEB J. 2016.
PMID: 27342765
Free PMC article.
Clinical Trial.
Genetic Variation in Choline-Metabolizing Enzymes Alters Choline Metabolism in Young Women Consuming Choline Intakes Meeting Current Recommendations.
Ganz AB, Cohen VV, Swersky CC, Stover J, Vitiello GA, Lovesky J, Chuang JC, Shields K, Fomin VG, Lopez YS, Mohan S, Ganti A, Carrier B, Malysheva OV, Caudill MA.
Ganz AB, et al. Among authors: lopez ys.
Int J Mol Sci. 2017 Jan 26;18(2):252. doi: 10.3390/ijms18020252.
Int J Mol Sci. 2017.
PMID: 28134761
Free PMC article.
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Effect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas: The RACECAT Randomized Clinical Trial.
Pérez de la Ossa N, Abilleira S, Jovin TG, García-Tornel Á, Jimenez X, Urra X, Cardona P, Cocho D, Purroy F, Serena J, San Román Manzanera L, Vivanco-Hidalgo RM, Salvat-Plana M, Chamorro A, Gallofré M, Molina CA, Cobo E, Davalos A, Ribo M; RACECAT Trial Investigators.
Pérez de la Ossa N, et al.
JAMA. 2022 May 10;327(18):1782-1794. doi: 10.1001/jama.2022.4404.
JAMA. 2022.
PMID: 35510397
Free PMC article.
Clinical Trial.
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