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3,653 results

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Page 1
Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization.
Herdman CA, Devkota L, Lin CM, Niu H, Strecker TE, Lopez R, Liu L, George CS, Tanpure RP, Hamel E, Chaplin DJ, Mason RP, Trawick ML, Pinney KG. Herdman CA, et al. Among authors: lopez r. Bioorg Med Chem. 2015 Dec 15;23(24):7497-520. doi: 10.1016/j.bmc.2015.10.012. Bioorg Med Chem. 2015. PMID: 26775540 Free PMC article.
Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents.
Devkota L, Lin CM, Strecker TE, Wang Y, Tidmore JK, Chen Z, Guddneppanavar R, Jelinek CJ, Lopez R, Liu L, Hamel E, Mason RP, Chaplin DJ, Trawick ML, Pinney KG. Devkota L, et al. Among authors: lopez r. Bioorg Med Chem. 2016 Mar 1;24(5):938-956. doi: 10.1016/j.bmc.2016.01.007. Epub 2016 Jan 6. Bioorg Med Chem. 2016. PMID: 26852340 Free PMC article.
Synthesis of a 2-aryl-3-aroyl indole salt (OXi8007) resembling combretastatin A-4 with application as a vascular disrupting agent.
Hadimani MB, Macdonough MT, Ghatak A, Strecker TE, Lopez R, Sriram M, Nguyen BL, Hall JJ, Kessler RJ, Shirali AR, Liu L, Garner CM, Pettit GR, Hamel E, Chaplin DJ, Mason RP, Trawick ML, Pinney KG. Hadimani MB, et al. Among authors: lopez r. J Nat Prod. 2013 Sep 27;76(9):1668-78. doi: 10.1021/np400374w. Epub 2013 Sep 9. J Nat Prod. 2013. PMID: 24016002 Free PMC article.
The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts.
Strecker TE, Odutola SO, Lopez R, Cooper MS, Tidmore JK, Charlton-Sevcik AK, Li L, MacDonough MT, Hadimani MB, Ghatak A, Liu L, Chaplin DJ, Mason RP, Pinney KG, Trawick ML. Strecker TE, et al. Among authors: lopez r. Cancer Lett. 2015 Dec 1;369(1):229-41. doi: 10.1016/j.canlet.2015.08.021. Epub 2015 Sep 1. Cancer Lett. 2015. PMID: 26325604 Free PMC article.
Demonstrating Tumor Vascular Disrupting Activity of the Small-Molecule Dihydronaphthalene Tubulin-Binding Agent OXi6196 as a Potential Therapeutic for Cancer Treatment.
Liu L, Schuetze R, Gerberich JL, Lopez R, Odutola SO, Tanpure RP, Charlton-Sevcik AK, Tidmore JK, Taylor EA, Kapur P, Hammers H, Trawick ML, Pinney KG, Mason RP. Liu L, et al. Among authors: lopez r. Cancers (Basel). 2022 Aug 30;14(17):4208. doi: 10.3390/cancers14174208. Cancers (Basel). 2022. PMID: 36077745 Free PMC article.
Chemiluminescent Probes for Imaging H2S in Living Animals.
Cao J, Lopez R, Thacker JM, Moon JY, Jiang C, Morris SN, Bauer JH, Tao P, Mason RP, Lippert AR. Cao J, et al. Among authors: lopez r. Chem Sci. 2015 Mar;6(3):1979-1985. doi: 10.1039/C4SC03516J. Chem Sci. 2015. PMID: 25709805 Free PMC article.
Expression of truncated products at the 5'-terminal region of RIPK2 and evolutive aspects that support their biological importance.
Villagra UMM, da Cunha BR, Polachini GM, Henrique T, Stefanini ACB, de Castro TB, da Silva CHTP, Feitosa OA, Fukuyama EE, López RVM, Dias-Neto E, Nunes FD, Severino P, Tajara EH. Villagra UMM, et al. Among authors: lopez rvm. Genome Biol Evol. 2024 May 16:evae106. doi: 10.1093/gbe/evae106. Online ahead of print. Genome Biol Evol. 2024. PMID: 38752399
Modeling the impact of sea level rise on endangered deer habitat.
Kim J, Popescu SC, Lopez RR, Wu XB, Silvy NJ. Kim J, et al. Among authors: lopez rr. J Environ Manage. 2024 May 14;360:121010. doi: 10.1016/j.jenvman.2024.121010. Online ahead of print. J Environ Manage. 2024. PMID: 38749135
3,653 results