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Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation.
Bates J, Vijayakumar A, Ghoshal S, Marchand B, Yi S, Kornyeyev D, Zagorska A, Hollenback D, Walker K, Liu K, Pendem S, Newstrom D, Brockett R, Mikaelian I, Kusam S, Ramirez R, Lopez D, Li L, Fuchs BC, Breckenridge DG. Bates J, et al. Among authors: lopez d. J Hepatol. 2020 Oct;73(4):896-905. doi: 10.1016/j.jhep.2020.04.037. Epub 2020 May 4. J Hepatol. 2020. PMID: 32376414 Free article.
Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression.
Guillot A, Winkler M, Silva Afonso M, Aggarwal A, Lopez D, Berger H, Kohlhepp MS, Liu H, Özdirik B, Eschrich J, Ma J, Peiseler M, Heymann F, Pendem S, Mahadevan S, Gao B, Diehl L, Gupta R, Tacke F. Guillot A, et al. Among authors: lopez d. Hepatology. 2023 Jul 1;78(1):150-166. doi: 10.1097/HEP.0000000000000270. Epub 2023 Jan 13. Hepatology. 2023. PMID: 36630995
ASK1/ p38 axis inhibition blocks the release of mitochondrial "danger signals" from hepatocytes and suppresses progression to cirrhosis and liver cancer.
Peng Z, Wei G, Huang P, Matta H, Gao W, An P, Zhao S, Lin Y, Tan L, Vaid K, Skelton-Badlani D, Nasser I, Budas G, Lopez D, Li L, Breckenridge D, Myers R, McHutchison J, Kuang M, Popov YV. Peng Z, et al. Among authors: lopez d. Hepatology. 2024 Feb 20. doi: 10.1097/HEP.0000000000000801. Online ahead of print. Hepatology. 2024. PMID: 38377458
Country-report pattern corrections of new cases allow accurate 2-week predictions of COVID-19 evolution with the Gompertz model.
Villanueva I, Conesa D, Català M, López Cano C, Perramon-Malavez A, Molinuevo D, de Rioja VL, López D, Alonso S, Cardona PJ, Montañola-Sales C, Prats C, Alvarez-Lacalle E. Villanueva I, et al. Among authors: lopez d. Sci Rep. 2024 May 11;14(1):10775. doi: 10.1038/s41598-024-61233-w. Sci Rep. 2024. PMID: 38730261 Free PMC article.
1,809 results