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Page 1
Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cruz-Lopez O, Lopez Cara C, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Gambari R, Ilaria L, Saletti R, Brancale A, Hamel E. Romagnoli R, et al. Among authors: lopez cara c. Bioorg Med Chem. 2008 Sep 15;16(18):8419-26. doi: 10.1016/j.bmc.2008.08.029. Epub 2008 Aug 17. Bioorg Med Chem. 2008. PMID: 18755591 Free PMC article.
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Preti D, Fruttarolo F, Pavani MG, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Balzarini J, Hadfield JA, Brancale A, Hamel E. Romagnoli R, et al. Among authors: lopez cara c. J Med Chem. 2007 May 3;50(9):2273-7. doi: 10.1021/jm070050f. Epub 2007 Apr 10. J Med Chem. 2007. PMID: 17419607
Symmetrical alpha-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation.
Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez Cara C, Carrion MD, Balzarini J, Hamel E, Basso G, Bortolozzi R, Viola G. Romagnoli R, et al. Among authors: lopez cara c. Bioorg Med Chem Lett. 2010 May 1;20(9):2733-9. doi: 10.1016/j.bmcl.2010.03.075. Epub 2010 Mar 25. Bioorg Med Chem Lett. 2010. PMID: 20378350 Free PMC article.
Synthesis and antitumor molecular mechanism of agents based on amino 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan: inhibition of tubulin and induction of apoptosis.
Romagnoli R, Baraldi PG, Lopez-Cara C, Cruz-Lopez O, Carrion MD, Kimatrai Salvador M, Bermejo J, Estévez S, Estévez F, Balzarini J, Brancale A, Ricci A, Chen L, Kim JG, Hamel E. Romagnoli R, et al. Among authors: lopez cara c. ChemMedChem. 2011 Oct 4;6(10):1841-53. doi: 10.1002/cmdc.201100279. Epub 2011 Aug 1. ChemMedChem. 2011. PMID: 21805646 Free PMC article.
One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazole: a unique, highly active antimicrotubule agent.
Romagnoli R, Baraldi PG, Lopez Cara C, Kimatrai Salvador M, Bortolozzi R, Basso G, Viola G, Balzarini J, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E. Romagnoli R, et al. Among authors: lopez cara c. Eur J Med Chem. 2011 Dec;46(12):6015-24. doi: 10.1016/j.ejmech.2011.10.013. Epub 2011 Oct 15. Eur J Med Chem. 2011. PMID: 22027100 Free PMC article.
Synthesis and biological effects of novel 2-amino-3-(4-chlorobenzoyl)-4-substituted thiophenes as allosteric enhancers of the A1 adenosine receptor.
Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Kimatrai Salvador M, Preti D, Aghazadeh Tabrizi M, Moorman AR, Vincenzi F, Borea PA, Varani K. Romagnoli R, et al. Among authors: lopez cara c. Eur J Med Chem. 2013 Sep;67:409-27. doi: 10.1016/j.ejmech.2013.07.002. Epub 2013 Jul 13. Eur J Med Chem. 2013. PMID: 23911855
Concise synthesis and biological evaluation of 2-Aroyl-5-amino benzo[b]thiophene derivatives as a novel class of potent antimitotic agents.
Romagnoli R, Baraldi PG, Lopez-Cara C, Preti D, Aghazadeh Tabrizi M, Balzarini J, Bassetto M, Brancale A, Fu XH, Gao Y, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G. Romagnoli R, et al. Among authors: lopez cara c. J Med Chem. 2013 Nov 27;56(22):9296-309. doi: 10.1021/jm4013938. Epub 2013 Nov 11. J Med Chem. 2013. PMID: 24164557 Free PMC article.
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
Romagnoli R, Baraldi PG, Lopez-Cara C, Salvador MK, Preti D, Tabrizi MA, Balzarini J, Nussbaumer P, Bassetto M, Brancale A, Fu XH, Yang-Gao, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G. Romagnoli R, et al. Among authors: lopez cara c. Bioorg Med Chem. 2014 Sep 15;22(18):5097-109. doi: 10.1016/j.bmc.2013.12.030. Epub 2013 Dec 24. Bioorg Med Chem. 2014. PMID: 24398384 Free PMC article.
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.
Romagnoli R, Baraldi PG, Salvador MK, Prencipe F, Lopez-Cara C, Schiaffino Ortega S, Brancale A, Hamel E, Castagliuolo I, Mitola S, Ronca R, Bortolozzi R, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: lopez cara c. J Med Chem. 2015 Apr 9;58(7):3209-22. doi: 10.1021/acs.jmedchem.5b00155. Epub 2015 Mar 26. J Med Chem. 2015. PMID: 25785605 Free PMC article.
14 results