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Discovery and structural characterization of chicoric acid as a SARS-CoV-2 nucleocapsid protein ligand and RNA binding disruptor.
Mercaldi GF, Bezerra EHS, Batista FAH, Tonoli CCC, Soprano AS, Shimizu JF, Nagai A, da Silva JC, Filho HVR, do Nascimento Faria J, da Cunha MG, Zeri ACM, Nascimento AFZ, Proenca-Modena JL, Bajgelman MC, Rocco SA, Lopes-de-Oliveira PS, Cordeiro AT, Bruder M, Marques RE, Sforça ML, Franchini KG, Benedetti CE, Figueira ACM, Trivella DBB. Mercaldi GF, et al. Among authors: lopes de oliveira ps. Sci Rep. 2022 Nov 2;12(1):18500. doi: 10.1038/s41598-022-22576-4. Sci Rep. 2022. PMID: 36323732 Free PMC article.
Structural dynamics of SARS-CoV-2 nucleocapsid protein induced by RNA binding.
Ribeiro-Filho HV, Jara GE, Batista FAH, Schleder GR, Costa Tonoli CC, Soprano AS, Guimarães SL, Borges AC, Cassago A, Bajgelman MC, Marques RE, Trivella DBB, Franchini KG, Figueira ACM, Benedetti CE, Lopes-de-Oliveira PS. Ribeiro-Filho HV, et al. Among authors: lopes de oliveira ps. PLoS Comput Biol. 2022 May 12;18(5):e1010121. doi: 10.1371/journal.pcbi.1010121. eCollection 2022 May. PLoS Comput Biol. 2022. PMID: 35551296 Free PMC article.
Extracellular matrix stiffness regulates degradation of MST2 via SCF βTrCP.
Fiore APZP, Rodrigues AM, Ribeiro-Filho HV, Manucci AC, de Freitas Ribeiro P, Botelho MCS, Vogel C, Lopes-de-Oliveira PS, Pagano M, Bruni-Cardoso A. Fiore APZP, et al. Among authors: lopes de oliveira ps. Biochim Biophys Acta Gen Subj. 2022 Dec;1866(12):130238. doi: 10.1016/j.bbagen.2022.130238. Epub 2022 Aug 28. Biochim Biophys Acta Gen Subj. 2022. PMID: 36044955 Free PMC article.
Nucleosome binding peptide presents laudable biophysical and in vivo effects.
Teles K, Fernandes V, Silva I, Leite M, Grisolia C, Lobbia VR, van Ingen H, Honorato R, Lopes-de-Oliveira P, Treptow W, Santos G. Teles K, et al. Biomed Pharmacother. 2020 Jan;121:109678. doi: 10.1016/j.biopha.2019.109678. Epub 2019 Nov 25. Biomed Pharmacother. 2020. PMID: 31810135 Free article.
Cryo-EM structure of the mature and infective Mayaro virus at 4.4 Å resolution reveals features of arthritogenic alphaviruses.
Ribeiro-Filho HV, Coimbra LD, Cassago A, Rocha RPF, Guerra JVDS, de Felicio R, Carnieli CM, Leme L, Padilha AC, Paes Leme AF, Trivella DBB, Portugal RV, Lopes-de-Oliveira PS, Marques RE. Ribeiro-Filho HV, et al. Among authors: lopes de oliveira ps. Nat Commun. 2021 May 24;12(1):3038. doi: 10.1038/s41467-021-23400-9. Nat Commun. 2021. PMID: 34031424 Free PMC article.
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