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A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants.
Modhiran N, Lauer SM, Amarilla AA, Hewins P, Lopes van den Broek SI, Low YS, Thakur N, Liang B, Nieto GV, Jung J, Paramitha D, Isaacs A, Sng JDJ, Song D, Jørgensen JT, Cheuquemilla Y, Bürger J, Andersen IV, Himelreichs J, Jara R, MacLoughlin R, Miranda-Chacon Z, Chana-Cuevas P, Kramer V, Spahn C, Mielke T, Khromykh AA, Munro T, Jones ML, Young PR, Chappell K, Bailey D, Kjaer A, Herth MM, Jurado KA, Schwefel D, Rojas-Fernandez A, Watterson D. Modhiran N, et al. Among authors: lopes van den broek si. iScience. 2023 Jun 9;26(7):107085. doi: 10.1016/j.isci.2023.107085. eCollection 2023 Jul 21. iScience. 2023. PMID: 37361875 Free PMC article.
Pretargeted imaging beyond the blood-brain barrier.
Shalgunov V, Lopes van den Broek S, Vang Andersen I, García Vázquez R, Raval NR, Palner M, Mori Y, Schäfer G, Herrmann B, Mikula H, Beschorner N, Nedergaard M, Syvänen S, Barz M, Moos Knudsen G, Battisti UM, Herth MM. Shalgunov V, et al. Among authors: lopes van den broek s. RSC Med Chem. 2022 Dec 2;14(3):444-453. doi: 10.1039/d2md00360k. eCollection 2023 Mar 22. RSC Med Chem. 2022. PMID: 36970152 Free PMC article.
Pretargeted Imaging beyond the Blood-Brain Barrier-Utopia or Feasible?
Lopes van den Broek S, Shalgunov V, García Vázquez R, Beschorner N, Bidesi NSR, Nedergaard M, Knudsen GM, Sehlin D, Syvänen S, Herth MM. Lopes van den Broek S, et al. Pharmaceuticals (Basel). 2022 Sep 27;15(10):1191. doi: 10.3390/ph15101191. Pharmaceuticals (Basel). 2022. PMID: 36297303 Free PMC article.
Bioorthogonal Click of Colloidal Gold Nanoparticles to Antibodies In vivo.
Poulie CBM, Sporer E, Hvass L, Jørgensen JT, Kempen PJ, Lopes van den Broek SI, Shalgunov V, Kjaer A, Jensen AI, Herth MM. Poulie CBM, et al. Among authors: lopes van den broek si. Chemistry. 2022 Nov 2;28(61):e202201847. doi: 10.1002/chem.202201847. Epub 2022 Sep 1. Chemistry. 2022. PMID: 35851967 Free PMC article.