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The impact of inosine on hippocampal synaptic transmission and plasticity involves the release of adenosine through equilibrative nucleoside transporters rather than the direct activation of adenosine receptors.
Valada P, Hinz S, Vielmuth C, Lopes CR, Cunha RA, Müller CE, Lopes JP. Valada P, et al. Among authors: lopes cr, lopes jp. Purinergic Signal. 2023 Jun;19(2):451-461. doi: 10.1007/s11302-022-09899-7. Epub 2022 Sep 26. Purinergic Signal. 2023. PMID: 36156760 Free PMC article.
Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine.
Gonçalves FQ, Lopes JP, Silva HB, Lemos C, Silva AC, Gonçalves N, Tomé ÂR, Ferreira SG, Canas PM, Rial D, Agostinho P, Cunha RA. Gonçalves FQ, et al. Among authors: lopes jp. Neurobiol Dis. 2019 Dec;132:104570. doi: 10.1016/j.nbd.2019.104570. Epub 2019 Aug 5. Neurobiol Dis. 2019. PMID: 31394204 Free article.
95 results