Lopes EA - Search Results

1

Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors.

Espadinha M, Lopes EA, Marques V, Amaral JD, Dos Santos DJVA, Mori M, Daniele S, Piccarducci R, Zappelli E, Martini C, Rodrigues CMP, Santos MMM. Espadinha M, et al. Among authors: lopes ea. Eur J Med Chem. 2022 Nov 5;241:114637. doi: 10.1016/j.ejmech.2022.114637. Epub 2022 Aug 5. Eur J Med Chem. 2022. PMID: 35961068 Free article.

2

An Update on MDMX and Dual MDM2/X Inhibitors.

Espadinha M, Barcherini V, Lopes EA, Santos MMM. Espadinha M, et al. Among authors: lopes ea. Curr Top Med Chem. 2018;18(8):647-660. doi: 10.2174/1568026618666180604080119. Curr Top Med Chem. 2018. PMID: 29866007 Review.

3

Small Molecules Targeting Mutant P53: A Promising Approach for Cancer Treatment.

Lopes EA, Gomes S, Saraiva L, Santos MMM. Lopes EA, et al. Curr Med Chem. 2019;26(41):7323-7336. doi: 10.2174/0929867325666181116124308. Curr Med Chem. 2019. PMID: 30444195 Review.

4

Potency and Selectivity Optimization of Tryptophanol-Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer.

Barcherini V, Almeida J, Lopes EA, Wang M, Magalhães E Silva D, Mori M, Wang S, Saraiva L, Santos MMM. Barcherini V, et al. Among authors: lopes ea. ChemMedChem. 2021 Jan 8;16(1):250-258. doi: 10.1002/cmdc.202000522. Epub 2020 Sep 2. ChemMedChem. 2021. PMID: 32737944 Free article.

5

Mutant p53 reactivator SLMP53-2 hinders ultraviolet B radiation-induced skin carcinogenesis.

Loureiro JB, Ribeiro R, Nazareth N, Ferreira T, Lopes EA, Gama A, Machuqueiro M, Alves MG, Marabini L, Oliveira PA, Santos MMM, Saraiva L. Loureiro JB, et al. Among authors: lopes ea. Pharmacol Res. 2022 Jan;175:106026. doi: 10.1016/j.phrs.2021.106026. Epub 2021 Dec 8. Pharmacol Res. 2022. PMID: 34890775

6

Discovery of spirooxadiazoline oxindoles with dual-stage antimalarial activity.

Lopes EA, Mestre R, Fontinha D, Legac J, Pei JV, Sanches-Vaz M, Mori M, Lehane AM, Rosenthal PJ, Prudêncio M, Santos MMM. Lopes EA, et al. Eur J Med Chem. 2022 Jun 5;236:114324. doi: 10.1016/j.ejmech.2022.114324. Epub 2022 Mar 28. Eur J Med Chem. 2022. PMID: 35390711

7

Antimalarial drugs: what's new in the patents?

Lopes EA, Santos MMM, Mori M. Lopes EA, et al. Expert Opin Ther Pat. 2023 Mar;33(3):151-168. doi: 10.1080/13543776.2023.2203814. Epub 2023 Apr 20. Expert Opin Ther Pat. 2023. PMID: 37060305 Review.

8

Hybrid molecules of protoflavones and spirooxindole derivatives with selective cytotoxicity against triple-negative breast cancer cells.

Girst G, Lopes EA, Gonçalves LM, Espadinha M, Kúsz N, Wang HC, Santos MMM, Hunyadi A. Girst G, et al. Among authors: lopes ea. RSC Med Chem. 2023 Aug 1;14(9):1778-1786. doi: 10.1039/d3md00251a. eCollection 2023 Sep 19. RSC Med Chem. 2023. PMID: 37731691 Free PMC article.

9

Material study of a liturgical cope from the 16th century.

Ferreira T, Moreiras H, Manhita A, Frade C, Lopes E, Tomaz P, Rodrigues PS, Mirão J, Dias C, Caldeira AT. Ferreira T, et al. Microsc Microanal. 2015 Oct 12:1-3. doi: 10.1017/S1431927615015299. Online ahead of print. Microsc Microanal. 2015. PMID: 26456031 No abstract available.

10

Enhanced white rot control in garlic bulbil using organic-inorganic hybrid materials as coating membranes.

Bessa LAM, Nazário MLF, Izumi CMS, Constantino VRL, Lourenço V Jr, Lopes EA, Mizubuti ESG, Tronto J. Bessa LAM, et al. Among authors: lopes ea. Dalton Trans. 2024 May 7;53(18):7880-7889. doi: 10.1039/d4dt00301b. Dalton Trans. 2024. PMID: 38634831

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