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Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors.
J Med Chem. 2021 Sep 23;64(18):13510-13523. doi: 10.1021/acs.jmedchem.1c00726. Epub 2021 Sep 1.
J Med Chem. 2021.
PMID: 34467758
Free PMC article.
Metabolism of a Kratom Alkaloid Metabolite in Human Plasma Increases Its Opioid Potency and Efficacy.
Kamble SH, León F, King TI, Berthold EC, Lopera-Londoño C, Siva Rama Raju K, Hampson AJ, Sharma A, Avery BA, McMahon LR, McCurdy CR.
Kamble SH, et al. Among authors: lopera londono c.
ACS Pharmacol Transl Sci. 2020 Jul 31;3(6):1063-1068. doi: 10.1021/acsptsci.0c00075. eCollection 2020 Dec 11.
ACS Pharmacol Transl Sci. 2020.
PMID: 33344889
Free PMC article.
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Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats.
Obeng S, Wilkerson JL, León F, Reeves ME, Restrepo LF, Gamez-Jimenez LR, Patel A, Pennington AE, Taylor VA, Ho NP, Braun T, Fortner JD, Crowley ML, Williamson MR, Pallares VLC, Mottinelli M, Lopera-Londoño C, McCurdy CR, McMahon LR, Hiranita T.
Obeng S, et al. Among authors: lopera londono c.
J Pharmacol Exp Ther. 2021 Mar;376(3):410-427. doi: 10.1124/jpet.120.000189. Epub 2020 Dec 31.
J Pharmacol Exp Ther. 2021.
PMID: 33384303
Free PMC article.
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