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Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction.
Tombor LS, John D, Glaser SF, Luxán G, Forte E, Furtado M, Rosenthal N, Baumgarten N, Schulz MH, Wittig J, Rogg EM, Manavski Y, Fischer A, Muhly-Reinholz M, Klee K, Looso M, Selignow C, Acker T, Bibli SI, Fleming I, Patrick R, Harvey RP, Abplanalp WT, Dimmeler S. Tombor LS, et al. Among authors: looso m. Nat Commun. 2021 Jan 29;12(1):681. doi: 10.1038/s41467-021-20905-1. Nat Commun. 2021. PMID: 33514719 Free PMC article.
The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice.
Rezende F, Moll F, Walter M, Helfinger V, Hahner F, Janetzko P, Ringel C, Weigert A, Fleming I, Weissmann N, Kuenne C, Looso M, Rieger MA, Nawroth P, Fleming T, Brandes RP, Schröder K. Rezende F, et al. Among authors: looso m. Redox Biol. 2018 May;15:12-21. doi: 10.1016/j.redox.2017.11.014. Epub 2017 Nov 22. Redox Biol. 2018. PMID: 29195137 Free PMC article.
Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.
Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, Looso M, Guenther A, Adelstein RS, Offermanns S, Stainier DYR. Kim HT, et al. Among authors: looso m. Nat Commun. 2018 Nov 2;9(1):4600. doi: 10.1038/s41467-018-06833-7. Nat Commun. 2018. PMID: 30389913 Free PMC article.
aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability.
Riddell M, Nakayama A, Hikita T, Mirzapourshafiyi F, Kawamura T, Pasha A, Li M, Masuzawa M, Looso M, Steinbacher T, Ebnet K, Potente M, Hirose T, Ohno S, Fleming I, Gattenlöhner S, Aung PP, Phung T, Yamasaki O, Yanagi T, Umemura H, Nakayama M. Riddell M, et al. Among authors: looso m. Nat Commun. 2018 Dec 17;9(1):5357. doi: 10.1038/s41467-018-07739-0. Nat Commun. 2018. PMID: 30559384 Free PMC article.
86 results