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Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus.
Llorente C, Jepsen P, Inamine T, Wang L, Bluemel S, Wang HJ, Loomba R, Bajaj JS, Schubert ML, Sikaroodi M, Gillevet PM, Xu J, Kisseleva T, Ho SB, DePew J, Du X, Sørensen HT, Vilstrup H, Nelson KE, Brenner DA, Fouts DE, Schnabl B. Llorente C, et al. Among authors: loomba r. Nat Commun. 2017 Oct 16;8(1):837. doi: 10.1038/s41467-017-00796-x. Nat Commun. 2017. PMID: 29038503 Free PMC article.
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.
Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M. Shalapour S, et al. Among authors: loomba r. Nature. 2017 Nov 16;551(7680):340-345. doi: 10.1038/nature24302. Epub 2017 Nov 8. Nature. 2017. PMID: 29144460 Free PMC article.
A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease.
Caussy C, Tripathi A, Humphrey G, Bassirian S, Singh S, Faulkner C, Bettencourt R, Rizo E, Richards L, Xu ZZ, Downes MR, Evans RM, Brenner DA, Sirlin CB, Knight R, Loomba R. Caussy C, et al. Among authors: loomba r. Nat Commun. 2019 Mar 29;10(1):1406. doi: 10.1038/s41467-019-09455-9. Nat Commun. 2019. PMID: 30926798 Free PMC article.
Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD.
Carvalho-Gontijo R, Han C, Zhang L, Zhang V, Hosseini M, Mekeel K, Schnabl B, Loomba R, Karin M, Brenner DA, Kisseleva T. Carvalho-Gontijo R, et al. Among authors: loomba r. Semin Liver Dis. 2022 Aug;42(3):233-249. doi: 10.1055/s-0042-1755316. Epub 2022 Aug 24. Semin Liver Dis. 2022. PMID: 36001995 Free PMC article. Review.
823 results