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A consortium-driven framework to guide the implementation of ICH M7 Option 4 control strategies.
Regul Toxicol Pharmacol. 2017 Nov;90:22-28. doi: 10.1016/j.yrtph.2017.08.008. Epub 2017 Aug 16.
Regul Toxicol Pharmacol. 2017.
PMID: 28822875
Understanding the degradation pathway of a poorly water-soluble drug formulated in PEG-400.
Kochling JD, Miao H, Young CR, Looker AR, Shannon M, Montgomery ER.
Kochling JD, et al. Among authors: looker ar.
J Pharm Biomed Anal. 2007 Apr 11;43(5):1638-46. doi: 10.1016/j.jpba.2006.12.011. Epub 2006 Dec 16.
J Pharm Biomed Anal. 2007.
PMID: 17224256
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Utilizing o-Quinone Methide Chemistry: Synthesis of d9-Ivacaftor.
Looker AR, Wilde N, Ryan MP, Roeper S, Ye Z, Lewandowski BL.
Looker AR, et al.
J Org Chem. 2020 Jan 17;85(2):501-507. doi: 10.1021/acs.joc.9b02552. Epub 2019 Dec 27.
J Org Chem. 2020.
PMID: 31846324
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Formation of 9,10-unsaturation in the mitomycins: facile fragmentation of beta-alkyl-beta-aryl-alpha-oxo-gamma-butyrolactones.
Ziegler FE, Berlin MY, Lee K, Looker AR.
Ziegler FE, et al. Among authors: looker ar.
Org Lett. 2000 Nov 16;2(23):3619-21. doi: 10.1021/ol000245g.
Org Lett. 2000.
PMID: 11073659
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